The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

Over the past decade, our view of human-associated microbes has expanded beyond that of
a few species toward an appreciation of the diverse and niche-specialized microbial …

Obesity is a global epidemic characterized by energy disequilibrium, metabolic disorder, fat
mass development, and chronic low-grade inflammation, which significantly affects the …

The intestinal microbiota has been implicated in insulin resistance, although evidence
regarding causality in humans is scarce. We therefore studied the effect of lean donor …

Changes in microbial diversity and composition are increasingly associated with several
disease states including obesity and behavioural disorders. Obesity-associated microbiota …

The parabrachial nucleus (PBN), which is located in the pons and is dissected by one of the
major cerebellar output tracks, is known to relay sensory information (visceral malaise, taste …

The Cre–lox recombination approach is commonly used to generate cell-specific gene
inactivation (or activation). We have noticed that the breeding and genotyping sections of …

The high comorbidity between obesity and mental disorders, such as depression and
anxiety, often exacerbates metabolic and neurological symptoms significantly. However …

Recent studies show a link between the gut microbiota and the regulation of satiety and
energy intake, processes that contribute to the development and pathophysiology of …

Abstract Activation of Agouti-Related Peptide (AgRP)-expressing neurons promotes feeding
and insulin resistance. Here, we examine the contribution of neuropeptide Y (NPY) …