Molecular alterations in meningioma: prognostic and therapeutic perspectives
The mutational landscape of meningioma has expanded following the use of the new
genetic sequencing approaches. Novel mutations have been characterized and reveal their …
genetic sequencing approaches. Novel mutations have been characterized and reveal their …
Multiple approaches converge on three biological subtypes of meningioma and extract new insights from published studies
JC Bayley, CC Hadley, AO Harmanci, AS Harmanci… - Science …, 2022 - science.org
One-fifth of meningiomas classified as benign by World Health Organization (WHO)
histopathological grading will behave malignantly. To better diagnose these tumors, several …
histopathological grading will behave malignantly. To better diagnose these tumors, several …
Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma
ST Magill, HN Vasudevan, K Seo… - Nature …, 2020 - nature.com
Meningiomas are the most common primary intracranial tumors, but the molecular drivers of
meningioma tumorigenesis are poorly understood. We hypothesized that investigating …
meningioma tumorigenesis are poorly understood. We hypothesized that investigating …
Discovering the molecular landscape of meningioma: the struggle to find new therapeutic targets
I Maggio, E Franceschi, V Di Nunno, L Gatto, A Tosoni… - Diagnostics, 2021 - mdpi.com
Meningiomas are the most common primary CNS tumors. They are usually benign but can
present aggressive behavior in about 20% of cases. The genetic landscape of meningioma …
present aggressive behavior in about 20% of cases. The genetic landscape of meningioma …
Deep learning model for the automated detection and histopathological prediction of meningioma
The volumetric assessment and accurate grading of meningiomas before surgery are highly
relevant for therapy planning and prognosis prediction. This study was to design a deep …
relevant for therapy planning and prognosis prediction. This study was to design a deep …
[HTML][HTML] Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome
HN Thirimanne, D Almiron-Bonnin, N Nuechterlein… - Cell genomics, 2024 - cell.com
Meningiomas, although mostly benign, can be recurrent and fatal. World Health
Organization (WHO) grading of the tumor does not always identify high-risk meningioma …
Organization (WHO) grading of the tumor does not always identify high-risk meningioma …
Predictors of postoperative seizure outcome in supratentorial meningioma
OBJECTIVE Meningiomas are the most common primary intracranial tumor. Seizures are
common sequelae of meningioma development. Meningioma patients with seizures can be …
common sequelae of meningioma development. Meningioma patients with seizures can be …
Gene expression analysis during progression of malignant meningioma compared to benign meningioma
OBJECTIVE Meningioma is the most common primary intracranial neoplasm. Only 1%–3%
of meningiomas are malignant according to the 2016 WHO criteria (WHO grade III). High …
of meningiomas are malignant according to the 2016 WHO criteria (WHO grade III). High …
Glutamine anaplerosis is required for amino acid biosynthesis in human meningiomas
Background We postulate that meningiomas undergo distinct metabolic reprogramming in
tumorigenesis and unraveling their metabolic phenotypes provide new therapeutic insights …
tumorigenesis and unraveling their metabolic phenotypes provide new therapeutic insights …
MPscore: a novel predictive and prognostic scoring for progressive meningioma
F Liu, J Qian, C Ma - Cancers, 2021 - mdpi.com
Simple Summary Subtyping for meningioma is urgently required to stratify the patients with
high risks of recurrence and progression due to the intertumoral heterogeneity in …
high risks of recurrence and progression due to the intertumoral heterogeneity in …