The mechanical properties of soft tissues play a key role in studying human injuries and their
mitigation strategies. While such properties are indispensable for computational modelling …

Current strategies of regenerative medicine are focused on the restoration of pathologically
altered tissue architectures by transplantation of cells in combination with supportive …

Biological materials found in living organisms, many of which are proteins, feature a
complex hierarchical organization. Type I collagen, a fibrous structural protein ubiquitous in …

Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

Polymers play an important role as excipients in any dosage form. They influence drug
release and should be stable, economic compatible, non-toxic, etc. They are broadly …

Implantable biomaterials that mimic the extracellular matrix (ECM) in key physical and
physiological functions require components and microarchitectures that are carefully …

Corneal transplantation is the treatment of choice for patients with advanced corneal
diseases. However, the outcome may be affected by graft rejection, high associated costs …

This article reviews the key developments in the tissue engineering field over the past
several years. The issues related to the development of the components of tissue …

Human corneal equivalents comprising the three main layers of the cornea (epithelium,
stroma, and endothelium) were constructed. Each cellular layer was fabricated from …

Purpose. To bioengineer a corneal surface replacement using ex vivo expanded, cultured
corneal epithelial stem cells seeded on a matrix derived from amniotic membrane and use …