Stimuli‐responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy

J Zhang, Y Lin, Z Lin, Q Wei, J Qian, R Ruan… - Advanced …, 2022 - Wiley Online Library
Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

Hybrid nanomaterials for cancer immunotherapy

J Li, W Lu, Y Yang, R Xiang, Y Ling, C Yu… - Advanced …, 2023 - Wiley Online Library
Nano‐immunotherapy has been recognized as a highly promising strategy for cancer
treatment in recent decades, which combines nanotechnology and immunotherapy to …

MOFs-based nanoagent enables dual mitochondrial damage in synergistic antitumor therapy via oxidative stress and calcium overload

W Bao, M Liu, J Meng, S Liu, S Wang, R Jia… - Nature …, 2021 - nature.com
Targeting subcellular organelle with multilevel damage has shown great promise for
antitumor therapy. Here, we report a core-shell type of nanoagent with iron (III) carboxylate …

An NIR Discrete Metallacycle constructed from Perylene Bisimide and Tetraphenylethylene Fluorophores for imaging‐guided cancer Radio‐chemotherapy

Y Ding, Z Tong, L Jin, B Ye, J Zhou, Z Sun… - Advanced …, 2022 - Wiley Online Library
To promote the clinical theranostic performances of platinum‐based anticancer drugs,
imaging capability is urgently desired, and their chemotherapeutic efficacy needs to be …

Systematic design of cell membrane coating to improve tumor targeting of nanoparticles

L Liu, D Pan, S Chen, MV Martikainen… - Nature …, 2022 - nature.com
Cell membrane (CM) coating technology is increasingly being applied in nanomedicine, but
the entire coating procedure including adsorption, rupture, and fusion is not completely …

Responsive biomaterials: optimizing control of cancer immunotherapy

L Xue, AS Thatte, D Mai, RM Haley, N Gong… - Nature Reviews …, 2024 - nature.com
Immunotherapy has emerged as an eminent and effective modality in the treatment of
cancer. However, current cancer immunotherapies lack spatial and temporal control …

Biocompatibility and biodegradability of metal organic frameworks for biomedical applications

N Singh, S Qutub, NM Khashab - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Metal organic frameworks (MOFs) are a unique class of smart hybrid materials that have
recently attracted significant interest for catalysis, separation and biomedical applications …

Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation

H Li, Q Luo, H Zhang, X Ma, Z Gu, Q Gong… - Chemical Society …, 2023 - pubs.rsc.org
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

Ultrathin Clay Nanoparticles‐Mediated Mutual Reinforcement of Ferroptosis and Cancer Immunotherapy

J Liu, J Zhan, Y Zhang, L Huang, J Yang… - Advanced …, 2024 - Wiley Online Library
Ferroptosis‐triggered immunogenic cell death (ICD) is widely adopted to potentiate the
body's antitumor immunity by catalyzing the production of toxic reactive oxygen species …

Cancer immunotherapy based on image-guided STING activation by nucleotide nanocomplex-decorated ultrasound microbubbles

X Li, S Khorsandi, Y Wang, J Santelli, K Huntoon… - Nature …, 2022 - nature.com
The cytosolic innate immune sensor cyclic GMP-AMP synthase-stimulator of interferon
genes (cGAS-STING) pathway is crucial for priming adaptive antitumour immunity through …