Quantitating the subtleties of microglial morphology with fractal analysis

A Karperien, H Ahammer, HF Jelinek - Frontiers in cellular …, 2013 - frontiersin.org
It is well established that microglial form and function are inextricably linked. In recent years,
the traditional view that microglial form ranges between “ramified resting” and “activated …

A healthy dose of chaos: Using fractal frameworks for engineering higher-fidelity biomedical systems

A Korolj, HT Wu, M Radisic - Biomaterials, 2019 - Elsevier
Optimal levels of chaos and fractality are distinctly associated with physiological health and
function in natural systems. Chaos is a type of nonlinear dynamics that tends to exhibit …

Iterative vessel segmentation of fundus images

S Roychowdhury, DD Koozekanani… - IEEE Transactions on …, 2015 - ieeexplore.ieee.org
This paper presents a novel unsupervised iterative blood vessel segmentation algorithm
using fundus images. First, a vessel enhanced image is generated by tophat reconstruction …

[HTML][HTML] Fractal dimensional analysis of optical coherence tomography angiography in eyes with diabetic retinopathy

S Zahid, R Dolz-Marco, KB Freund… - … & visual science, 2016 - tvst.arvojournals.org
Purpose: We used fractal dimensional analysis to analyze retinal vascular disease burden in
eyes with diabetic retinopathy using spectral-domain optical coherence tomography …

Genetic algorithm based feature selection combined with dual classification for the automated detection of proliferative diabetic retinopathy

RA Welikala, MM Fraz, J Dehmeshki, A Hoppe… - … Medical Imaging and …, 2015 - Elsevier
Proliferative diabetic retinopathy (PDR) is a condition that carries a high risk of severe visual
impairment. The hallmark of PDR is the growth of abnormal new vessels. In this paper, an …

Automated detection of proliferative diabetic retinopathy using a modified line operator and dual classification

RA Welikala, J Dehmeshki, A Hoppe, V Tah… - Computer methods and …, 2014 - Elsevier
Proliferative diabetic retinopathy (PDR) is a condition that carries a high risk of severe visual
impairment. The hallmark of PDR is neovascularisation, the growth of abnormal new …

Design and 3D printing of hydrogel scaffolds with fractal geometries

J Warner, P Soman, W Zhu, M Tom… - … Biomaterials Science & …, 2016 - ACS Publications
Structures that exhibit fractal geometries are typically self-similar and iterative. Fractal
patterns appear in nature as approximations of mathematical abstractions, yet exist as …

Canadian Ophthalmological Society evidence-based clinical practice guidelines for the management of diabetic retinopathy

P Hooper, MC Boucher, A Cruess, KG Dawson… - Canadian Journal of …, 2012 - Elsevier
Methods An English-language literature search for the years 1997–2010 was conducted
using PubMed, EMBASE, the Cochrane Library, the National Guideline Clearing House, and …

Quantitative analysis of vascular colonisation and angio-conduction in porous silicon-substituted hydroxyapatite with various pore shapes in a chick chorioallantoic …

A Magnaudeix, J Usseglio, M Lasgorceix, F Lalloue… - Acta biomaterialia, 2016 - Elsevier
The development of scaffolds for bone filling of large defects requires an understanding of
angiogenesis and vascular guidance, which are crucial processes for bone formation and …

Fractal, multifractal, and lacunarity analysis of microglia in tissue engineering

AL Karperien, HF Jelinek - Frontiers in bioengineering and …, 2015 - frontiersin.org
Tissue engineering is currently one of the most exciting fields in biology (Grayson et al.,
2009). Fractal analysis is equally exciting (Di Ieva et al., 2013), as is the study of microglia …