RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Structurally diverse pyridinium salts are quite familiar structures in many natural products
and bioactive pharmaceuticals. Over the centuries, these privileged scaffolds have played …

Cationic compounds are promising candidates for development of antimicrobial agents.
Positive charges attached to surfaces, particles, polymers, peptides or bilayers have been …

Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

Gene therapy, as a promising therapeutics to treat genetic or acquired diseases, has
achieved exciting development in the past two decades. Appropriate gene vectors can be …

A key end goal of gene delivery research is to develop clinically relevant vectors that can be
used to combat elusive diseases such as AIDS. Despite promising engineering strategies …

The ability to safely and efficiently transfer foreign DNA into cells is a fundamental goal in
biotechnology. Toward this end, rapid advances have recently been made in our …

Gene therapy has emerged as a promising approach for the treatment or prevention of
acquired and genetic diseases. At the present time, major somatic gene transfer approaches …

Supramolecular binary vesicles based on the host–guest complexation of water-soluble
pillar [6] arene (WP6) and SAINT molecule have been successfully constructed, which …

RNA is emerging as a potential therapeutic modality for the treatment of incurable diseases.
Despite intense research, the advent to clinical utility remains compromised by numerous …