New insights regarding genetic aspects of childhood obesity: a minireview

CO Mǎrginean, C Mǎrginean, LE Meliţ - Frontiers in pediatrics, 2018 - frontiersin.org
Introduction: Childhood obesity is occurring at alarming rates in both developed and
developing countries.“Obesogenic” environmental factors must be associated with variants …

The relationship between daytime napping and obesity: a systematic review and meta-analysis

Z Cai, Y Yang, J Zhang, Y Liu - Scientific Reports, 2023 - nature.com
Daytime napping, a habit widely adopted globally, has an unclear association with obesity.
In this study, we executed a meta-analysis to explore the relationship between daytime …

Early inflammatory status related to pediatric obesity

CO Mărginean, LE Meliţ, DV Ghiga… - Frontiers in …, 2019 - frontiersin.org
Background: Obese individuals are often in a chronic inflammatory condition due to the
malfunction of immune-related activities in the adipose tissue, involving a transient …

The adipokines and inflammatory status in the era of pediatric obesity

CO Mărginean, LE Meliţ, A Huțanu, DV Ghiga… - Cytokine, 2020 - Elsevier
Introduction Obesity is associated with a chronic inflammation due to the deficiency in
immune activity related to adipose tissue. A wide-spectrum of pro-inflammatory cytokines …

Prebiotics, probiotics, and synbiotics—a research hotspot for pediatric obesity

R Borka Balas, LE Meliț, A Lupu, VV Lupu… - Microorganisms, 2023 - mdpi.com
Childhood obesity is a major public health problem worldwide with an increasing
prevalence, associated not only with metabolic syndrome, insulin resistance, hypertension …

Effects of PPARG and PPARGC1A gene polymorphisms on obesity markers

C Muntean, MO Sasaran, A Crisan… - Frontiers in Public …, 2022 - frontiersin.org
Pediatric obesity presents a multifactorial etiology, which involves genetic traits as well,
including single nucleotide polymorphisms. The aim of the study is to investigate the …

The Yin-Yang concept of pediatric obesity and gut microbiota

LE Meliț, CO Mărginean, MO Săsăran - Biomedicines, 2022 - mdpi.com
The era of pediatric obesity is no longer a myth. Unfortunately, pediatric obesity has reached
alarming incidence levels worldwide and the factors that contribute to its development have …

The assessment of liver fibrosis in children with obesity on two methods: transient and two dimensional shear wave elastography

CO Mărginean, LE Meliţ, DV Ghiga, MO Săsăran - Scientific Reports, 2019 - nature.com
The aim of this study was to assess the liver stiffness values in children with obesity versus
healthy children on 2D-SWE and TE taking into account different laboratory parameters. We …

The usefulness of inflammatory biomarkers in diagnosing child and adolescent's gastritis: STROBE compliant article

LE Meliţ, MO Mărginean, S Mocan, CO Mărginean - Medicine, 2019 - journals.lww.com
Neutrophil to lymphocyte ratio (NLR) is a simple, noninvasive, inexpensive inflammatory
marker that can useful in the assessment of inflammatory activity, especially in pediatric …

Systemic inflammatory status–a bridge between gestational weight gain and neonatal outcomes (STROBE-compliant article)

C Rugină, CO Mărginean, LE Meliţ, A Huţanu… - Medicine, 2021 - journals.lww.com
Systemic inflammatory status – a bridge between gestational... : Medicine Systemic
inflammatory status – a bridge between gestational weight gain and neonatal outcomes (STROBE-compliant …