Selecting a TNT schedule in locally advanced rectal cancer: can we predict who actually benefits?

C Aschele, R Glynne-Jones - Cancers, 2023 - mdpi.com
Simple Summary Total neoadjuvant therapy is a strategy developed to improve the efficacy
of chemotherapy in locally advanced rectal cancer by anticipating all the chemotherapy …

Elderly Rectal Cancer: An Updated Review

CK Huang, CH Shih, YS Kao - Current Oncology Reports, 2024 - Springer
Abstract Purpose of Review Treatment of rectal cancer patients of advanced age should be
modulated by life expectancy and tolerance. Due to the rapid advance of this field, we aim to …

The conditioning of adjuvant chemotherapy for stage II and III rectal cancer determined by postoperative pathological characteristics in Romania

HD Liscu, BR Liscu, R Mitre, IV Anghel… - Medicina, 2023 - mdpi.com
The management of locally advanced rectal cancer (LARC) suffered changes thanks to the
development of improved surgical procedures, radiation delivery, and chemotherapy …

Predicting mortality and recurrence in colorectal cancer: Comparative assessment of predictive models

S Alinia, M Asghari-Jafarabadi, L Mahmoudi… - Heliyon, 2024 - cell.com
Introduction Colorectal cancer (CRC), also known as colorectal cancer, is a significant
disease marked by high fatality rates, ranking as the third leading cause of global mortality …

Identification of age‐and immune‐related gene signatures for clinical outcome prediction in lung adenocarcinoma

A Zhou, D Zhang, X Kang, JD Brooks - Cancer Medicine, 2023 - Wiley Online Library
Background The understanding of the factors causing decreased overall survival (OS) in
older patients compared to younger patients in lung adenocarcinoma (LUAD) remains …

Optimized machine learning model for predicting unplanned reoperation after rectal cancer anterior resection

Y Su, Y Li, W Yang, X Luo, L Chen - European Journal of Surgical Oncology, 2024 - Elsevier
Background Unplanned reoperation (URO) after surgery adversely affects the quality of life
and prognosis of patients undergoing anterior resection for rectal cancer. This study aims to …

Immunotherapy and radiotherapy for older patients with locally advanced rectal cancer unfit for surgery or decline surgery: a practical proposal by the International …

NP Nguyen, M Mohammadianpanah… - Frontiers in …, 2024 - frontiersin.org
The standard of care for locally advanced rectal cancer is total neoadjuvant therapy followed
by surgical resection. Current evidence suggests that selected patients may be able to delay …

Survival prognostic in different age groups of patients undergoing local versus radical excision for rectal cancer: a study based on the SEER database

J Li, L Wen, Y Ma, G Zhang, P Wang, C Huang… - Updates in Surgery, 2024 - Springer
Age significantly affects the prognosis of patients with rectal cancer after radical excision
(RE), and local excision (LE) is an alternative surgical procedure to RE. To compare the …

Factors associated with one-year mortality after curative surgery for primary clinical T4 and locally recurrent rectal cancer in elderly patients

NCM van Ham, S Glazemakers… - European Journal of …, 2024 - Elsevier
Introduction Despite advancements in colorectal cancer care, one-year post-operative
mortality rates remain high for elderly patients who have undergone curative surgery for …

Construction of a Novel RNA Prognostic-Predicting Model for Rectum Adenocarcinoma by Bioinformatics Analysis

L Zhu, X Lu, C Jiao, N Gu, Y Zhu - Journal of Biomedical …, 2023 - ingentaconnect.com
We aimed to construct and validate a prognostic-predicting model of rectum
adenocarcinoma (READ) based on RNA-binding protein-related genes (RBPGs) by …