The gut microbiome as a modulator of healthy ageing
The gut microbiome is a contributory factor in ageing-related health loss and in several non-
communicable diseases in all age groups. Some age-linked and disease-linked …
communicable diseases in all age groups. Some age-linked and disease-linked …
Applications of machine learning in human microbiome studies: a review on feature selection, biomarker identification, disease prediction and treatment
LJ Marcos-Zambrano… - Frontiers in …, 2021 - frontiersin.org
The number of microbiome-related studies has notably increased the availability of data on
human microbiome composition and function. These studies provide the essential material …
human microbiome composition and function. These studies provide the essential material …
Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma
The composition of the gut microbiome has been associated with clinical responses to
immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific …
immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific …
Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals
The gut microbiome is shaped by diet and influences host metabolism; however, these links
are complex and can be unique to each individual. We performed deep metagenomic …
are complex and can be unique to each individual. We performed deep metagenomic …
Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer
Association studies have linked microbiome alterations with many human diseases.
However, they have not always reported consistent results, thereby necessitating cross …
However, they have not always reported consistent results, thereby necessitating cross …
Species-level functional profiling of metagenomes and metatranscriptomes
Functional profiles of microbial communities are typically generated using comprehensive
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …
Gut microbiome, big data and machine learning to promote precision medicine for cancer
The gut microbiome has been implicated in cancer in several ways, as specific microbial
signatures are known to promote cancer development and influence safety, tolerability and …
signatures are known to promote cancer development and influence safety, tolerability and …
The human oral microbiome in health and disease: from sequences to ecosystems
JR Willis, T Gabaldón - Microorganisms, 2020 - mdpi.com
The human oral cavity is home to an abundant and diverse microbial community (ie, the oral
microbiome), whose composition and roles in health and disease have been the focus of …
microbiome), whose composition and roles in health and disease have been the focus of …
Extensive impact of non-antibiotic drugs on human gut bacteria
A few commonly used non-antibiotic drugs have recently been associated with changes in
gut microbiome composition, but the extent of this phenomenon is unknown. Here, we …
gut microbiome composition, but the extent of this phenomenon is unknown. Here, we …
Faecal microbiome-based machine learning for multi-class disease diagnosis
Systemic characterisation of the human faecal microbiome provides the opportunity to
develop non-invasive approaches in the diagnosis of a major human disease. However …
develop non-invasive approaches in the diagnosis of a major human disease. However …