Arguments based on cell energetics favour the view that a mitochondrion capable of
oxidative phosphorylation was a prerequisite for the evolution of other features of the …

Giardia lamblia is a widespread parasitic protist with a complex MT cytoskeleton that is
critical for motility, attachment, mitosis and cell division, and transitions between its two life …

The trypanosomatid Angomonas deanei is a model to study endosymbiosis. Each cell
contains a single β-proteobacterial endosymbiont that divides at a defined point in the host …

Protists have evolved a myriad of highly specialized cytoskeletal organelles that expand
known functional capacities of microtubule (MT) polymers. One such innovation–the ventral …

Giardia lamblia, a widespread parasitic protozoan, attaches to the host gastrointestinal
epithelium by using the ventral disc, a complex microtubule (MT) organelle. The 'cup …

Giardia lamblia is a flagellated parasite of the gut and causes significant morbidity
worldwide. Novel druggable targets are sorely needed due to Giardia's prevalence and the …

Cytokinesis, or the division of the cytoplasm, following the end of mitosis or meiosis, is
accomplished in animal cells, fungi, and amoebae, by the constriction of an actomyosin …

Protists are an exceptionally diverse group of mostly single-celled eukaryotes. The
organization of the microtubular cytoskeleton in protists from various evolutionary lineages …

Animals and amoebae assemble actin/spectrin-based plasma membrane skeletons, forming
what is often called the cell cortex, whereas euglenids and alveolates (ciliates …

Metazoans evolved from a single protist lineage. While all eukaryotes share a conserved
actin and tubulin‐based cytoskeleton, it is commonly perceived that intermediate filaments …