Introduction Similar to other tissues, the dental pulp mounts an inflammatory reaction as a
way to eliminate pathogens and stimulate repair. Pulp inflammation is prerequisite for dentin …

A new source of mesenchymal stem cells has recently been discovered, the so-called dental
pulp derived stem cells (DPSCs) which therefore could represent potentially tools for …

Human dental pulp contains precursor cells termed dental pulp stem cells (DPSC) that show
self-renewal and multilineage differentiation and also secrete multiple proangiogenic and …

The primary goal of regenerative endodontics is to restore the vitality and functions of the
dentin-pulp complex, as opposed to filing of the root canal with bioinert materials. A myriad …

Insulin-like growth factor 1 (IGF-1) plays an important role in the regulation of tooth root
development, and stem cells from apical papilla (SCAPs) are responsible for the formation of …

Aim To quantify the expression of calcitonin gene‐related peptide (CGRP), substance P
(SP), neurokinin A (NKA), neuropeptide Y (NPY) and vasoactive intestinal polypeptide (VIP) …

Creating an optimal microenvironment that supports angiogenesis, cell-cell cross talk, cell
migration, and differentiation is crucial for pulp/dentin regeneration. It was shown that dental …

The GH/IGF axis is a major regulator of bone formation and resorption and is essential to the
achievement of normal skeleton growth and homeostasis. Beyond its key role in bone …

Human dental pulp cells (DPCs), which are known to contain a subset of stem cells capable
of reforming a dentin and pulp-like complex upon in vivo transplantation, were isolated from …

Introduction: The implantation of mesenchymal stem cells (MSCs) has been shown to exert
benefits for the survival of the zone-of-stasis. However, the clinical experience indicates the …