Increasing evidence suggests that abnormal cerebral glucose metabolism is largely present
in Alzheimer's disease (AD). The brain utilizes glucose as its main energy source and a …

Alzheimer's disease (AD) is a complex neurodegenerative disease in the elderly and the
most common cause of human dementia. AD is characterized by accumulation of abnormal …

Abnormalities in brain glucose metabolism and accumulation of abnormal protein deposits
called plaques and tangles are neuropathological hallmarks of Alzheimer's disease (AD) …

Plant extracts are rich in bioactive compounds, such as polyphenols, sesquiterpenes, and
triterpenes, which potentially have antiviral activities. As a consequence of the coronavirus …

The in vitro panel of technologies to address biomolecular interactions are in play, however
microscale thermophoresis is continuously increasing in use to represent a key player in this …

Abstract Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that
sustains proteostasis network under a large variety of physiopathological conditions. Its …

The process of choosing the most proper technique for studying the molecular interactions is
based on critical factors such as instrumentation complexity, automation, experimental …

A common symptom in Alzheimer's disease (AD) is cognitive decline, of which the potential
pathogenesis remains unclear. In order to understand the mechanism of gut microbiota in …

Biomolecular condensates are membraneless organelles (MLOs) that form dynamic,
chemically distinct subcellular compartments organizing macromolecules such as proteins …

Most proteins undergo posttranslational modification such as acetylation, methylation,
phosphorylation, biotinylation, and ubiquitination to regulate various cellular processes …