Tumors strongly depend on their surrounding tumor microenvironment (TME) for growth and
progression, since stromal elements are required to generate the optimal conditions for …

Prostate cancer (PCa) is by far the most commonly diagnosed cancer in men worldwide.
Despite sensitivity to androgen deprivation, patients with advanced disease eventually …

Current risk-stratification systems for prostate cancer (PCa) do not sufficiently reflect the
disease heterogeneity. Genomic classifiers (GC) enable improved risk stratification after …

Simple Summary The crosstalk between prostate stroma and its epithelium is essential to
tissue homeostasis. Likewise, reciprocal signaling between tumor cells and the stromal …

Prostate cancer progression is significantly affected by its tumor microenvironment, in which
mesenchymal cells play a crucial role. Stromal cells are modified by cancer mutations …

Background: It remains a challenge to effectively treat prostate cancer (PCa) that affects
global men's health. It is essential to find a natural alternative drug and explore its antitumor …

Ovarian cancer (OC) is the deadliest gynecological cancer in women. Immune cell infiltration
has a critical role in regulating carcinogenesis and prognosis in OC. To identify prognostic …

Background The tumor microenvironment and intercellular communication between solid
tumors and the surrounding stroma play crucial roles in cancer initiation, progression, and …

The initial management of potentially oligometastatic hormone sensitive prostate cancer has
been complicated by rapid advances in the field. Clinically, subgroup analyses of two …

Immune infiltration of ovarian cancer (OV) is a critical factor in determining patient's
prognosis. Using data from TCGA and GTEx database combined with WGCNA and …