MicroRNAs (miRNAs) are endogenous∼ 23 nt RNAs that play important gene-regulatory roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their …
The recent discoveries of microRNAs (miRNAs) and characterization of the first few targets of their gene products in Caenorhabditis elegans and Drosophila melanogaster have set the …
M Inui, G Martello, S Piccolo - Nature reviews Molecular cell biology, 2010 - nature.com
MicroRNAs (miRNAs) are integral elements in the post-transcriptional control of gene expression. After the identification of hundreds of miRNAs, the challenge is now to …
Micro RNAs are a large family of noncoding RNAs of 21–22 nucleotides whose functions are generally unknown. Here a large subset of Drosophila micro RNAs is shown to be perfectly …
YS Lee, K Nakahara, JW Pham, K Kim, Z He… - Cell, 2004 - cell.com
Abstract The RNase III enzyme Dicer processes RNA into siRNAs and miRNAs, which direct a RNA-induced silencing complex (RISC) to cleave mRNA or block its translation (RNAi) …
I Alvarez-Garcia, EA Miska - 2005 - journals.biologists.com
Five years into thesmall RNA revolution'it is hard not to share in the excitement about the rapidly unravelling biology of microRNAs. Since the discovery of the first microRNA gene, lin …
Since the establishment of a canonical animal microRNA biogenesis pathway driven by the RNase III enzymes Drosha and Dicer, an unexpected variety of alternative mechanisms that …
Vive la différence: biogenesis and evolution of microRNAs in plants and animals | Genome Biology Skip to main content SpringerLink Account Menu Find a journal Publish with us Track …
S Bagga, J Bracht, S Hunter, K Massirer, J Holtz… - Cell, 2005 - cell.com
MicroRNAs (miRNAs) are∼ 22 nucleotide RNAs that negatively regulate the expression of protein-coding genes. In a present model of miRNA function in animals, miRNAs that form …