Angiogenesis in prostate cancer: onset, progression and imaging

G Russo, M Mischi, W Scheepens… - BJU …, 2012 - Wiley Online Library
What's known on the subject? and What does the study add? Today, angiogenesis is known
to play a key role in cancer growth and development. Emerging cancer treatments are based …

Interferon α in cancer immunoediting: From elimination to escape

P Vidal - Scandinavian Journal of Immunology, 2020 - Wiley Online Library
Interferon α (IFNα) is a cytokine that mediates diverse immune responses to tumours. It is the
oldest immune‐based oncologic drug and has been widely used to treat various …

The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction

SG Thacker, CC Berthier, D Mattinzoli… - The journal of …, 2010 - journals.aai.org
Systemic lupus erythematosus (SLE) is characterized by increased vascular risk due to
premature atherosclerosis independent of traditional risk factors. We previously proposed …

miR-221-3p regulates VEGFR2 expression in high-risk prostate cancer and represents an escape mechanism from sunitinib in vitro

M Krebs, AG Solimando, C Kalogirou… - Journal of Clinical …, 2020 - mdpi.com
Downregulation of miR-221-3p expression in prostate cancer (PCa) predicted overall and
cancer-specific survival of high-risk PCa patients. Apart from PCa, miR-221-3p expression …

Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-γ

I Tietzel, C El-Haibi, RA Carabeo - PloS one, 2009 - journals.plos.org
Chlamydiae are obligate intracellular pathogens that are sensitive to pro-inflammatory
cytokine interferon-γ. IFN-γ-inducible murine p47 GTPases have been demonstrated to …

Interferon-α as angiogenesis inhibitor: learning from tumor models

S Indraccolo - Autoimmunity, 2010 - Taylor & Francis
Interferon-α (IFN-α), a cytokine with marked therapeutic activity in transplantable tumor
models, has been identified as powerful angiogenesis inhibitor. The effects of IFN-α on the …

Distinct prognostic value of mRNA expression of guanylate-binding protein genes in skin cutaneous melanoma

Q Wang, X Wang, Q Liang, S Wang… - Oncology …, 2018 - spandidos-publications.com
The purpose of the present study was to assess if guanylate-binding protein (GBP) mRNAs
could be prognostic biomarkers for patients with skin cutaneous melanoma (SKCM). The …

Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) model: A good alternative to study PCa progression and chemoprevention approaches

LA Kido, C de Almeida Lamas, MR Maróstica Jr… - Life sciences, 2019 - Elsevier
The use of genetically modified animals has been studied in scientific research over time as
a way to discover new treatments or even a cure for various diseases. Transgenic …

Reprogramming T lymphocytes for melanoma adoptive immunotherapy by T-cell receptor gene transfer with lentiviral vectors

S Bobisse, M Rondina, A Merlo, V Tisato… - Cancer research, 2009 - AACR
T-cell receptor (TCR) gene transfer for cancer immunotherapy is limited by the availability of
large numbers of tumor-specific T cells. TCR α and β chains were isolated from a highly lytic …

Interferon γ-induced human guanylate binding protein 1 inhibits mammary tumor growth in mice

K Lipnik, E Naschberger, N Gonin-Laurent… - Molecular …, 2010 - Springer
Interferon γ (IFN-γ) has recently been implicated in cancer immunosurveillance. Among the
most abundant proteins induced by IFN-γ are guanylate binding proteins (GBPs), which …