Autophagy-regulating microRNAs and cancer

D Gozuacik, Y Akkoc, DG Ozturk, M Kocak - Frontiers in oncology, 2017 - frontiersin.org
Macroautophagy (autophagy herein) is a cellular stress response and a survival pathway
that is responsible for the degradation of long-lived proteins, protein aggregates, as well as …

[HTML][HTML] The interaction between miRNAs/lncRNAs and Notch pathway in human disorders

S Ghafouri-Fard, MC Glassy, A Abak… - Biomedicine & …, 2021 - Elsevier
Notch pathway is a signaling cascade with important impacts on cell proliferation,
differentiation, developmental processes and tissue homeostasis. This pathway also …

Sirtuins and their influence on autophagy

MW Baeken - Journal of Cellular Biochemistry, 2024 - Wiley Online Library
Sirtuins and autophagy are well‐characterized agents that can promote longevity and
protect individual organisms from age‐associated diseases like neurodegenerative …

LncRNA NEAT1 affects inflammatory response by targeting miR-129-5p and regulating Notch signaling pathway in epilepsy

Y Wan, ZQ Yang - Cell Cycle, 2020 - Taylor & Francis
It is crucial to understand the molecular mechanisms involved in epileptogenesis. This study
aims to investigate the role of lncRNA NEAT1, miR-129-5p and Notch signaling pathway in …

The emergence of noncoding RNAs as Heracles in autophagy

J Zhang, P Wang, L Wan, S Xu, D Pang - Autophagy, 2017 - Taylor & Francis
Macroautophagy/autophagy is a catabolic process that is widely found in nature. Over the
past few decades, mounting evidence has indicated that noncoding RNAs, ranging from …

Non-coding RNAs and glioma: Focus on cancer stem cells

A Rajabi, M Kayedi, S Rahimi, F Dashti… - Molecular Therapy …, 2022 - cell.com
Glioblastoma and gliomas can have a wide range of histopathologic subtypes. These
heterogeneous histologic phenotypes originate from tumor cells with the distinct functions of …

Lnc RNA MALAT 1/miR‐129 axis promotes glioma tumorigenesis by targeting SOX 2

Z Xiong, L Wang, Q Wang… - Journal of cellular and …, 2018 - Wiley Online Library
We aimed to explore the interaction among lnc RNA MALAT 1, miR‐129 and SOX 2.
Besides, we would investigate the effect of MALAT 1 on the proliferation of glioma stem cells …

Targeting epigenetic mechanisms of resistance to chemotherapy in gliomas

P Skouras, M Markouli, I Papadatou, C Piperi - Critical Reviews in …, 2024 - Elsevier
Glioma, an aggressive type of brain tumors of glial origin is highly heterogeneous, posing
significant treatment challenges due to its intrinsic resistance to conventional therapeutic …

Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation

Z Tao, T Li, H Ma, Y Yang, C Zhang, L Hai, P Liu… - Cell Death & …, 2018 - nature.com
Autophagy is a vital process that involves degradation of long-lived proteins and
dysfunctional organelles and contributes to cellular metabolism. Glioma-initiating cells …

MicroRNA-129 in human cancers: from tumorigenesis to clinical treatment

Y Gao, B Feng, S Han, L Lu, Y Chen, X Chu… - Cellular Physiology and …, 2016 - karger.com
Emerging evidence has shown that microRNAs (miRNAs) play essential roles in regulating
human cancers development and progression. However, the underlying mechanisms …