Objective To examine whether sperm DNA fragmentation has an effect on pregnancy and
miscarriage after IVF and/or intracytoplasmic sperm injection (ICSI). Design Systematic …

OBJECTIVE: To review the mechanisms responsible for DNA fragmentation in human
sperm, including those occurring during spermatogenesis and transport through the …

BACKGROUND Chemotherapy treatment in premenopausal women is associated with an
increased risk of premature ovarian failure (POF) but the exact mechanism through which …

BACKGROUND Cryopreservation has been extensively used in assisted reproductive
technology, agriculture and conservation programmes for endangered species. The …

Sperm DNA integrity is essential for the accurate transmission of genetic information. It has a
highly compact and complex structure and is capable of decondensation—features that must …

BACKGROUND ICSI is currently the most commonly used assisted reproductive technology,
accounting for 70–80% of the cycles performed. This extensive use, even excessive, is partly …

Concentration, motility and morphology are parameters commonly used to determine the
fertilization potential of an ejaculate. These parameters give a general view on the quality of …

Cryopreservation is of interest not only for fish farming but also for the conservation and
genetic improvement of resources. This technique has been well established in some …

BACKGROUND Sperm DNA damage is common amongst infertile men and may adversely
impact natural reproduction, IUI-assisted reproduction and to a lesser degree IVF …

BACKGROUND Diabetes mellitus (DM) is increasing in men of reproductive age. Despite
this, the prevalence of diabetes in men attending fertility clinics is largely unknown …