Pyrimidines and their hybrid molecules have continued to be a favorable area for organic
chemists owing to their richness in natural and synthetic compounds with multifarious …

Cancer is a major cause of deaths across the globe due to chemoresistance and lack of
selective chemotherapy. Pyrido [2, 3-d] pyrimidine is an emerging scaffold in medicinal …

The present method provides a wide scope and quick access to dihydropyrido [2, 3-d: 6, 5-
d′] dipyrimidinetetraone and pyrimido [4, 5-d] pyrimidine derivatives in good to excellent …

Synthesis of a new series of 20 compounds bearing the thieno [2, 3-d] pyrimidine-4-one
scaffold was achieved. The inhibitory activity of these compounds was performed over 60 …

Journal of Chemical and Pharmaceutical Research, 2016, 8(3):734-772 Review Article The
chemistry of pyrido[2,3-d]pyrimidines Page 1 www.jocpr.com Available online Journal of …

A convenient metal-free synthesis of unsymmetrical 2-aminopyrimidines from imidazolate
enaminones has been developed. In this procedure, various structural 2-aminopyrimidines …

A facile and efficient catalyst-and oxidant-free multicomponent synthesis of a small library of
highly substituted pyrido [2, 3-d] pyrimidine derivatives is reported. The products were …

In this work, we report the efficient synthesis of novel (hydroxybenzoyl) pyrido [2, 3-d]
pyrimidine heterocycle derivatives: 6-(2-hydroxy-5-methylbenzoyl)-1-methylpyrido [2, 3-d] …

In this work, we report an efficient synthesis of pyrimidine fused novel 4-phenyl-2-thioxo-3, 4-
dihydro-1H-pyrido [1, 2-a] pyrimido [4, 5-d] pyrimidin-5 (2H)-one. The chemical structure of …

Methods were developed for the synthesis of new pyrido [2, 3-d] pyrimidine and pyrimidino
[4, 5-d][1, 3] oxazine derivatives. When heated under reflux with MeONa in BuOH, 5-acetyl-4 …