Dendritic cells (DCs), the most efficient antigen-presenting cells, are necessary for the
effective activation of naïve T cells. DCs can also acquire tolerogenic functions in vivo and in …

Acetylation is one of the major post-translational protein modifications in the cell, with
manifold effects on the protein level as well as on the metabolome level. The acetyl group …

Epigenetic aberrations, which are recognized as key drivers of several human diseases, are
often caused by genetic defects that result in functional deregulation of epigenetic proteins …

There is now an abundance of evidence to show that short-chain fatty acids (SCFAs) play an
important role in the maintenance of health and the development of disease. SCFAs are a …

Abstract Histone deacetylase 11 (HDAC11), a sole member of the class IV HDAC subfamily,
participates in various cardiovascular diseases. Recent evidence showed that pyroptosis …

Histone dacetylases (HDACs) are a group of enzymes that remove acetyl groups from
histones and regulate expression of tumor suppressor genes. They are implicated in many …

Background This review focuses on exosomes derived from various cancer cells. The review
discusses the possibility of differentiating macrophages in alternatively activated anti …

Staphylococcus aureus is a leading cause of biofilm-associated prosthetic joint infection
(PJI), resulting in considerable disability and prolonged treatment. It is known that host …

Microglial cells are the resident macrophages in the central nervous system. These cells of
mesodermal/mesenchymal origin migrate into all regions of the central nervous system …

Extensive transcriptional and ontogenetic diversity exists among normal tissue-resident
macrophages, with unique transcriptional profiles endowing the cells with tissue-specific …