Inflammasomes in cancer: a double-edged sword

R Kolb, GH Liu, AM Janowski, FS Sutterwala… - Protein & …, 2014 - academic.oup.com
Chronic inflammatory responses have long been observed to be associated with various
types of cancer and play decisive roles at different stages of cancer development …

Gastric acid, calcium absorption, and their impact on bone health

S Kopic, JP Geibel - Physiological reviews, 2013 - journals.physiology.org
Calcium balance is essential for a multitude of physiological processes, ranging from cell
signaling to maintenance of bone health. Adequate intestinal absorption of calcium is a …

Interleukin-1 polymorphisms associated with increased risk of gastric cancer

EM El-Omar, M Carrington, WH Chow, KEL McColl… - Nature, 2000 - nature.com
Helicobacter pylori infection is associated with a variety of clinical outcomes including
gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but …

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

Z Sun, CW Arendt, W Ellmeier, EM Schaeffer… - Nature, 2000 - nature.com
Productive interaction of a T lymphocyte with an antigen-presenting cell results in the
clustering of the T-cell antigen receptor (TCR) and the recruitment of a large signalling …

Helicobacter pylori and Interleukin 1 Genotyping: An Opportunity to Identify High-Risk Individuals for Gastric Carcinoma

C Figueiredo, JC Machado, P Pharoah… - Journal of the …, 2002 - academic.oup.com
Abstract Background: Both Helicobacter pylori genotype and host genetic polymorphisms
play a role in determining the clinical consequences of H. pylori infection. We investigated …

The importance of interleukin 1β inHelicobacter pylori associated disease

EM El-Omar - Gut, 2001 - gut.bmj.com
Helicobacter pylori infection is associated with divergent clinical outcomes that range from
simple asymptomatic gastritis to more serious conditions such as peptic ulcer disease and …

Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma

JC Machado, P Pharoah, S Sousa, R Carvalho… - Gastroenterology, 2001 - Elsevier
Background & Aims: Interleukin (IL)-1 gene cluster proinflammatory polymorphisms have
been associated with development of gastric atrophy and with increased risk of gastric …

Local Cytokine Response in Helicobacter pylori-Infected Subjects

C Lindholm, M Quiding-Jarbrink, H Lonroth… - Infection and …, 1998 - Am Soc Microbiol
The host immune response to Helicobacter pylori infection might be of importance with
regard to the outcome of infection by this organism, eg, to explain why only a proportion of …

[HTML][HTML] Factors that mediate colonization of the human stomach by Helicobacter pylori

C Dunne, B Dolan, M Clyne - World Journal of Gastroenterology …, 2014 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) colonizes the stomach of humans and causes chronic
infection. The majority of bacteria live in the mucus layer overlying the gastric epithelial cells …

Pro-and anti-inflammatory cytokines gene polymorphisms and Helicobacter pylori infection: interactions influence outcome

CF Zambon, D Basso, F Navaglia, C Belluco, A Falda… - Cytokine, 2005 - Elsevier
The aim of this study was to evaluate whether there was any correlation between
Helicobacter pylori-associated diseases and (1) H. pylori virulence genes or (2) IL-1B, IL …