The aim of the present article was to review the current knowledge on the prognostic value
of tumour marker in the treatment of oral squamous cell carcinoma (OSCC). The literature of …

Objective: To evaluate the degree of expression of cyclin-D1, p27 and p63 in mild, moderate
and severe dysplasia using immunohistochemical evaluation in order to illustrate their …

A small proportion of cases diagnosed as oral lichen planus (OLP) and oral lichenoid
lesions (OLL) can undergo malignant transformation. Some authors, however, stand that …

Aim: To study expression of p53 protein and ki-67 antigen in normal, non-dysplastic,
dysplastic, premalignant and malignant lesions of the oral mucosa. Materials and Methods …

Background: Akt is a serine/threonine kinase that plays an important role in tumorigenesis
and influences prognosis in several cancers. However, its importance in oral squamous cell …

The potential for malignant transformation of oral lichen planus is still controversial. The
expression of proteins related to cell proliferation and apoptosis in oral lichen planus and …

Several malignant tumours accumulate hyaluronan (HA), a matrix component suggested to
promote cancer cell growth and migration. The expression and prognostic value of HA was …

In this study an attempt was made to establish the significance of a battery of molecular
alterations and thereby identify risk predictors in oral carcinogenesis. For this purpose …

BACKGROUND: The B cell lymphoma-2 gene is a proto-oncogene whose protein product
inhibits apoptosis. Its role is associated with keeping cells alive, but not by stimulating them …

OBJECTIVES: Mutation of the p53 gene and overexpression of its protein are frequent in
human cancer, suggesting that these events play a critical role in the onset or progression of …