Noble metals in medicine: Latest advances

S Medici, M Peana, VM Nurchi, JI Lachowicz… - Coordination Chemistry …, 2015 - Elsevier
History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …

Nanopharmaceuticals as a solution to neglected diseases: Is it possible?

GA Islan, M Durán, ML Cacicedo, G Nakazato… - Acta tropica, 2017 - Elsevier
The study of neglected diseases has not received much attention, especially from public and
private institutions over the last years, in terms of strong support for developing treatment for …

A novel palladium (II) antitumor agent: Synthesis, characterization, DFT perspective, CT-DNA and BSA interaction studies via in-vitro and in-silico approaches

M Feizi-Dehnayebi, E Dehghanian… - … Acta Part A: Molecular …, 2021 - Elsevier
Since numerous people annually pass away due to cancer, research in this field is essential.
Thus a newly made and water like palladium (II) complex of formula [Pd (phen)(acac)] NO 3 …

Antimicrobial and antitumor activity of S-methyl dithiocarbazate Schiff base zinc (II) complexes

F Ramilo-Gomes, Y Addis, I Tekamo, I Cavaco… - Journal of Inorganic …, 2021 - Elsevier
Schiff bases (SB) obtained from S-methyl dithiocarbazate and aromatic aldehydes:
salicylaldehyde (H 2 L 1), o-vanillin (H 2 L 2), pyridoxal (H 2 L 3) and 2, 6-diformyl-4 …

Searching for new chemotherapies for tropical diseases: Ruthenium–clotrimazole complexes display high in vitro activity against Leishmania major and Trypanosoma …

A Martínez, T Carreon, E Iniguez… - Journal of medicinal …, 2012 - ACS Publications
Eight new ruthenium complexes of clotrimazole (CTZ) with high antiparasitic activity have
been synthesized, cis, fac-[RuIICl2 (DMSO) 3 (CTZ)](1), cis, cis, trans-[RuIICl2 (DMSO) 2 …

New insight into the structural, electrochemical and biological aspects of macroacyclic Cu (II) complexes derived from S-substituted dithiocarbazate schiff bases

ML Low, L Maigre, MIM Tahir, ERT Tiekink… - European journal of …, 2016 - Elsevier
Copper (II) complexes synthesized from the products of condensation of S-methyl-and S-
benzyldithiocarbazate with 2, 5-hexanedione (SMHDH2 and SBHDH2 respectively) have …

Gold (III) complexes in medicinal chemistry

PI da Silva Maia, VM Deflon, U Abram - Future medicinal chemistry, 2014 - Taylor & Francis
A number of gold (III) compounds has been designed with the objective of overcoming the
disadvantages associated with the platinum-based drugs for cancer treatment. Compounds …

Mixed ligand palladium (II) complexes of 6-methoxy-2-oxo-1, 2-dihydroquinoline-3-carbaldehyde 4 N-substituted thiosemicarbazones with triphenylphosphine co …

E Ramachandran, DS Raja, NSP Bhuvanesh… - Dalton …, 2012 - pubs.rsc.org
A series of new 6-methoxy-2-oxo-1, 2-dihydroquinoline-3-carbaldehyde 4N-substituted
thiosemicarbazone ligands (H2L1–H2L5) and their corresponding palladium (II) complexes …

From Benznidazole to new drugs: Nanotechnology contribution in Chagas disease

DC Gomes, TS Medeiros, EL Alves Pereira… - International Journal of …, 2023 - mdpi.com
Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Benznidazole and nifurtimox are the two approved drugs for their treatment, but both …

Conjugation of a new series of dithiocarbazate Schiff base copper (II) complexes with vectors selected to enhance antibacterial activity

ML Low, L Maigre, P Dorlet, R Guillot… - Bioconjugate …, 2014 - ACS Publications
A new series of six Schiff bases derived from S-methyldithiocarbazate (SMDTC) and S-
benzyldithiocarbazate (SBDTC) with methyl levulinate (SMML, SBML), levulinic acid (SMLA …