PPARγ 在脂肪生成中的遗传和表观遗传调控
崔婷婷， 邢天宇， 褚衍凯， 李辉， 王宁 - 遗传, 2017 - chinagene.cn
过氧化物酶体增殖物激活受体γ (peroxisome proliferator-activated receptor gamma, PPARγ)
是脂肪生成和脂肪组织发育的关键调控因子, 另外在糖脂代谢, 炎症和免疫反应等多种生物学 …
是脂肪生成和脂肪组织发育的关键调控因子, 另外在糖脂代谢, 炎症和免疫反应等多种生物学 …
Genome-wide survey identifies TNNI2 as a target of KLF7 that inhibits chicken adipogenesis via downregulating FABP4
Y Sun, H Xu, J Li, M Peng, Z Jia, L Kong… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Krüppel-like factor 7 (KLF7) negatively regulates adipocyte differentiation; however, the
mechanism underlying its activity in mammals and birds remains poorly understood. To …
mechanism underlying its activity in mammals and birds remains poorly understood. To …
Knockout and restoration reveal differential functional roles of PPARγ1 and PPARγ2 in chicken adipogenesis
Y Jing, F Mu, X Xing, J Huang, M Lou… - Journal of Agricultural …, 2022 - ACS Publications
Peroxisome proliferator-activated receptor γ (PPARγ) is the master regulator of
adipogenesis and is expressed as two isoforms, PPARγ1 and PPARγ2. Our previous …
adipogenesis and is expressed as two isoforms, PPARγ1 and PPARγ2. Our previous …
[HTML][HTML] Peroxisome proliferator-activated receptor γ isoforms differentially regulate preadipocyte proliferation, apoptosis, and differentiation in chickens
F Mu, Y Jing, B Ning, J Huang, T Cui, Y Guo, X You… - Poultry science, 2020 - Elsevier
Peroxisome proliferator-activated receptor γ (PPARγ) has 2 protein isoforms (PPARγ1 and
PPARγ2) generated by alternative promoter usage and alternative splicing. However, their …
PPARγ2) generated by alternative promoter usage and alternative splicing. However, their …
Ghrelin is a signal to facilitate the utilization of fatty acids and save glucose by the liver, skeletal muscle, and adipose tissues in chicks
X Song, M Wang, H Jiao, J Zhao, X Wang… - Biochimica et Biophysica …, 2022 - Elsevier
Ghrelin, classically known as a central appetite-stimulating hormone, has recently been
recognized to play an important role in peripheral tissue energy metabolism. In chicken …
recognized to play an important role in peripheral tissue energy metabolism. In chicken …
KLF2 inhibits chicken preadipocyte differentiation at least in part via directly repressing PPARγ transcript variant 1 expression
T Cui, J Huang, Y Sun, B Ning, F Mu, X You… - Frontiers in Cell and …, 2021 - frontiersin.org
Peroxisome proliferator-activated receptor gamma (PPAR γ) is the master regulatory factor
of preadipocyte differentiation. As a result of alternative splicing and alternative promoter …
of preadipocyte differentiation. As a result of alternative splicing and alternative promoter …
[HTML][HTML] E2F transcription factor 5, a new regulator in adipogenesis to mediate the role of Krüppel-like factor 7 in chicken preadipocyte differentiation and proliferation
Z Jia, Z Jin, M Li, X Zhang, M Peng, S Zhang, M Tan… - Poultry Science, 2024 - Elsevier
ABSTRACT E2F transcription factor 5 (E2F5) gene is a transcription factor, plays an
important role in the development of a variety of cells. E2F5 is expressed in human and …
important role in the development of a variety of cells. E2F5 is expressed in human and …
Nuclear respiratory factor 1 negatively regulates the P1 promoter of the peroxisome proliferator-activated receptor-γ gene and inhibits chicken adipogenesis
T Cui, T Xing, J Huang, F Mu, Y Jin, X You… - Frontiers in …, 2018 - frontiersin.org
Peroxisome proliferator-activated receptor-γ (PPARγ) is a master regulator of adipogenesis,
and alterations in its function are associated with various pathological processes related to …
and alterations in its function are associated with various pathological processes related to …
[HTML][HTML] DNA methylation promotes the expression of PPARγ transcript 1 at least in part by preventing NRF1 binding to the promoter P1 of chicken PPARγ gene
TT Cui, JX Huang, BL Ning, F Mu, HY Chen, TY Xing… - Poultry Science, 2024 - Elsevier
Peroxisome proliferator-activated receptor gamma (PPARγ) is a master regulator of
adipogenesis. Our previous study revealed that chicken PPARγ has 3 alternative promoters …
adipogenesis. Our previous study revealed that chicken PPARγ has 3 alternative promoters …
NOTCH1 as a Negative Regulator of Avian Adipocyte Differentiation: Implications for Fat Deposition
Z Wang, Y Su, M Zhao, Z Ma, J Li, Z Hou, H Li - Animals, 2024 - mdpi.com
Simple Summary Excessive abdominal fat deposition significantly impacts feed efficiency
and meat yield of chicken, which is closely associated with adipocyte differentiation …
and meat yield of chicken, which is closely associated with adipocyte differentiation …