Amplification and suppression of traveling waves along the mouse organ of Corti: evidence for spatial variation in the longitudinal coupling of outer hair cell-generated …

JB Dewey, BE Applegate, JS Oghalai - Journal of Neuroscience, 2019 - Soc Neuroscience
Mammalian hearing sensitivity and frequency selectivity depend on a mechanical
amplification process mediated by outer hair cells (OHCs). OHCs are situated within the …

Nonlinearity and amplification in cochlear responses to single and multi-tone stimuli

E Fallah, CE Strimbu, ES Olson - Hearing research, 2019 - Elsevier
Mechanical displacements of the basilar membrane (BM) and the electrophysiological
responses of the auditory outer hair cells (OHCs) are key components of the frequency …

Interplay between traveling wave propagation and amplification at the apex of the mouse cochlea

A Nankali, CA Shera, BE Applegate, JS Oghalai - Biophysical Journal, 2022 - cell.com
Sounds entering the mammalian ear produce waves that travel from the base to the apex of
the cochlea. An electromechanical active process amplifies traveling wave motions and …

A role for tectorial membrane mechanics in activating the cochlear amplifier

A Nankali, Y Wang, CE Strimbu, ES Olson, K Grosh - Scientific Reports, 2020 - nature.com
The mechanical and electrical responses of the mammalian cochlea to acoustic stimuli are
nonlinear and highly tuned in frequency. This is due to the electromechanical properties of …

Cochlear impulse responses resolved into sets of gammatones: the case for beating of closely spaced local resonances

A Bell, HP Wit - PeerJ, 2018 - peerj.com
Gammatones have had a long history in auditory studies, and recent theoretical work
suggests they may play an important role in cochlear mechanics as well. Following this lead …

[HTML][HTML] Prediction and interpretation of rare missense variant in OTOG associated with hearing loss

M Askari, Z Moradi, M Mohammadi, M Lagzian… - Genomics, 2021 - Elsevier
OTOG encodes for otogelin, a component of the tectorial membrane. This gene is associated
with nonprogressive mild-to-moderate hearing loss. However, no studies have yet identified …

[引用][C] The sensitivity of the cochlear amplifier to changes in operating conditions

Y Wang - 2019 - Columbia University