The immunology of pregnancy is complex and poorly defined. During the complex process
of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in …

Preeclampsia is a complex cardiovascular disorder of pregnancy with underlying
multifactorial pathogeneses; however, its etiology is not fully understood. It is characterized …

Macrophages are a subset of mononuclear phagocytes of the innate immune system with
high plasticity and heterogeneity. At the maternal–fetal interface, macrophages are present …

Macrophages (MФs) are the leukocytes produced from differentiation of monocytes and are
located in almost all tissues of human body. They are involved in various processes, such as …

Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …

BACKGROUND Human pregnancy requires robust hemostasis to prevent hemorrhage
during extravillous trophoblast (EVT) invasion of the decidualized endometrium, modification …

During pregnancy, the maternal immune system is challenged by the presence of the fetus,
which must be tolerated despite being semiallogeneic. Uterine mucosal (or decidual) …

Preeclampsia (PE) is an important, common, and dangerous complication of pregnancy; it
causes maternal and perinatal illness and is responsible for a high proportion of maternal …

Macrophages are key components of the innate immune system and exhibit extensive
plasticity and heterogeneity. They play a significant role in the non-pregnant cycling uterus …

In normal human placentation, uterine invasion by trophoblast cells and subsequent spiral
artery remodeling depend on cooperation among fetal trophoblasts and maternal decidual …