Age-related macular degeneration (AMD) is the most common cause of blindness among
the elderly in the developed world. While treatment is effective for the neovascular or “wet” …

The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Age-related macular degeneration (AMD) is a significant cause of vision loss in the elderly.
The extent to which epigenetic changes regulate AMD progression is unclear. Here we …

Age‐related macular degeneration (AMD) is a multifactorial disease of the retina featured by
degeneration and loss of photoreceptors and retinal pigment epithelium (RPE) cells with …

Age-related macular degeneration (AMD) is a degenerative disease of the human retina
affecting individuals over the age of 55 years. This heterogeneous condition arises from a …

Biomarkers can help unravel mechanisms of disease and identify new targets for therapy.
They can also be useful in clinical practice for monitoring disease progression, evaluation of …

Age-related macular degeneration (AMD) is a complex, multifactorial, progressive retinal
disease that affects millions of people worldwide and has become the leading cause of …

Age-related macular degeneration (AMD) is the leading cause of severe irreversible central
vision loss in individuals over 65 years old. Genome-wide association studies (GWASs) …

Complex biological processes, such as organogenesis and homeostasis, are stringently
regulated by genetic programs that are fine-tuned by epigenetic factors to establish cell fates …

Multifaceted and divergent manifestations across tissues and cell types have curtailed
advances in deciphering the cellular events that accompany advanced age and contribute to …