Physiology of cell volume regulation in vertebrates

EK Hoffmann, IH Lambert… - Physiological …, 2009 - journals.physiology.org
The ability to control cell volume is pivotal for cell function. Cell volume perturbation elicits a
wide array of signaling events, leading to protective (eg, cytoskeletal rearrangement) and …

Functional significance of cell volume regulatory mechanisms

F Lang, GL Busch, M Ritter, H Volkl… - Physiological …, 1998 - journals.physiology.org
Lang, Florian, Gillian L. Busch, Markus Ritter, Harald Völkl, Siegfried Waldegger, Erich
Gulbins, and Dieter Häussinger. Functional Significance of Cell Volume Regulatory …

A fresh look at reperfusion injury

HM Piper, D Garcña-Dorado… - Cardiovascular research, 1998 - academic.oup.com
In clinical therapy of evolving acute myocardial infarction, coronary reperfusion has proven
to be the only way to limit infarct size, provided it occurs soon enough after coronary artery …

The Changing Face of the Na+/H+ Exchanger, NHE1: Structure, Regulation, and Cellular Actions

LK Putney, SP Denker, DL Barber - Annual review of …, 2002 - annualreviews.org
The NHE family of ion exchangers includes six isoforms (NHE1–NHE6) that function in an
electroneutral exchange of intracellular H+ for extracellular Na+. This review focuses on the …

Cell volume regulation: osmolytes, osmolyte transport, and signal transduction

F Wehner, H Olsen, H Tinel, E Kinne-Saffran… - Reviews of physiology …, 2003 - Springer
In recent years, it has become evident that the volume of a given cell is an important factor
not only in defining its intracellular osmolality and its shape, but also in defining other …

Molecular physiology of vertebrate Na+/H+ exchangers

S Wakabayashi, M Shigekawa… - Physiological …, 1997 - journals.physiology.org
This review describes recent progress concerning the molecular aspects of the Na+/H+
exchanger. The Na+/H+ exchanger is an important regulator for intracellular pH, cell volume …

The role of glutamate in neuronal ischemic injury: the role of spark in fire

BB Kostandy - Neurological Sciences, 2012 - Springer
Although being a physiologically important excitatory neurotransmitter, glutamate plays a
pivotal role in various neurological disorders including ischemic neurological diseases. Its …

Membrane mechanisms and intracellular signalling in cell volume regulation

EK Hoffmann, PB Dunham - International review of cytology, 1995 - Elsevier
Recent work on selected aspects of the cellular and molecular physiology of cell volume
regulation is reviewed. First, the physiological significance of the regulation of cell volume is …

The expanding family of eucaryotic Na+/H+ exchangers

L Counillon, J Pouysségur - Journal of Biological Chemistry, 2000 - ASBMB
Maintaining intracellular pH values close to neutrality is a crucial task for a wide variety of
cells. Hence, various mechanisms for pH regulation have been selected early in evolution …

Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume

S Waldegger, P Barth, G Raber… - Proceedings of the …, 1997 - National Acad Sciences
Hepatic metabolism and gene expression are among other regulatory mechanisms
controlled by the cellular hydration state, which changes rapidly in response to anisotonicity …