Clinical Perspectives and Novel Preclinical Models of Malignant Pleural Mesothelioma: A Critical Review

A Ebrahimi, G Ak, C Özel, H İzgördü… - ACS Pharmacology & …, 2024 - ACS Publications
Pleural mesothelioma (PM), a rare malignant tumor explicitly associated with asbestos and
erionite exposures, has become a global health problem due to limited treatment options …

Clinical studies with anti–CTLA-4 antibodies in non-melanoma indications

L Calabrò, R Danielli, L Sigalotti, M Maio - Seminars in oncology, 2010 - Elsevier
Available medical treatments have limited impact on the survival of patients with advanced
cancer; therefore, new therapeutic strategies able to generate more effective host's immune …

[HTML][HTML] A nuclear grading system is a strong predictor of survival in epitheloid diffuse malignant pleural mesothelioma

K Kadota, K Suzuki, C Colovos, CS Sima, VW Rusch… - Modern Pathology, 2012 - Elsevier
Epithelioid mesothelioma is the most prevalent subtype of diffuse malignant pleural
mesothelioma in which only staging is prognostic for survival. In this study of epithelioid …

[HTML][HTML] Inflammation-based prognostic indices in malignant pleural mesothelioma

DJ Pinato, FA Mauri, R Ramakrishnan, L Wahab… - Journal of Thoracic …, 2012 - Elsevier
Introduction Chronic inflammation plays a key role in the pathogenesis of malignant pleural
mesothelioma (MPM) as a result of asbestos exposure. Biomarkers of systemic inflammation …

[HTML][HTML] Pleomorphic epithelioid diffuse malignant pleural mesothelioma: a clinicopathological review and conceptual proposal to reclassify as biphasic or …

K Kadota, K Suzuki, CS Sima, VW Rusch… - Journal of Thoracic …, 2011 - Elsevier
Introduction In patients with epithelioid diffuse malignant pleural mesothelioma (DMPM),
clinical stage is the current primary prognostic factor. We sought to investigate whether …

Turkey national mesothelioma surveillance and environmental asbestos exposure control program

S Metintaş, HF Batırel, H Bayram, Ü Yılmaz… - International Journal of …, 2017 - mdpi.com
Malignant mesothelioma (MM) is an important health problem due to ongoing asbestos
exposure. Environmental asbestos exposure leads to a high risk of MM in Turkey. The …

Prognosis and prognostic factors of patients with mesothelioma: a population-based study

S van der Bij, H Koffijberg, JA Burgers, P Baas… - British journal of …, 2012 - nature.com
Background: It is important to regularly update survival estimates of patients with malignant
mesothelioma as prognosis may vary according to epidemiologic factors and diagnostic and …

High systemic immune–inflammation index represents an unfavorable prognosis of malignant pleural mesothelioma

M Ma, N Yu, B Wu - Cancer management and research, 2019 - Taylor & Francis
Background: Malignant pleural mesothelioma (MPM) represents a fatal disease with high
aggressiveness, and limited biomarkers have yet been identified for MPM. The present study …

[HTML][HTML] Prognostic significance of soluble mesothelin in malignant pleural mesothelioma: a meta-analysis

L Tian, R Zeng, X Wang, C Shen, Y Lai, M Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Soluble mesothelin is beneficial to detect the progression and the treatment
response of malignant pleural mesothelioma. However, the prognostic value of soluble …

[HTML][HTML] Pulmonary asbestos fiber burden is related to patient survival in malignant pleural mesothelioma

S Laaksonen, E Kettunen, E Sutinen, I Ilonen… - Journal of Thoracic …, 2022 - Elsevier
Introduction Malignant pleural mesothelioma (MPM) is associated with poor prognosis and
is strongly associated with occupational asbestos exposure. Given the importance of …