Spectroscopy and molecular simulation on the interaction of Nano-Kaempferol prepared by oil-in-water with two carrier proteins: An investigation of protein–protein …

M Kaffash, S Tolou-Shikhzadeh-Yazdi… - … Acta Part A: Molecular …, 2024 - Elsevier
In this work, the interaction of human serum albumin (HSA) and human holo-transferrin
(HTF) with the prepared Nano-Kaempferol (Nano-KMP) through oil-in-water procedure was …

Cytotoxic species in amyloid-associated diseases: Oligomers or mature fibrils

MK Siddiqi, S Malik, N Majid, P Alam… - Advances in protein …, 2019 - Elsevier
Amyloid diseases especially, Alzheimer's disease (AD), is characterized by an imbalance
between the production and clearance of amyloid-β (Aβ) species. Amyloidogenic proteins or …

[HTML][HTML] Exploring the interaction of bioactive kaempferol with serum albumin, lysozyme and hemoglobin: A biophysical investigation using multi-spectroscopic …

S Das, Z Hazarika, S Sarmah, K Baruah… - … of Photochemistry and …, 2020 - Elsevier
In recent years research based on kaempferol (KMP) has shown its potential therapeutic
applications in medicinal chemistry and clinical biology. Therefore, to understand its …

Investigation of inhibitory potential of quercetin to the pyruvate dehydrogenase kinase 3: Towards implications in anticancer therapy

R Dahiya, T Mohammad, S Roy, S Anwar… - International journal of …, 2019 - Elsevier
Abstract Pyruvate dehydrogenase kinase 3 (PDK3) is a mitochondrial protein, has recently
been considered as a potential pharmacological target for varying types of cancer. Here, we …

A comprehensive spectroscopic and computational investigation on the binding of the anti-asthmatic drug triamcinolone with serum albumin

S Siddiqui, F Ameen, I Jahan, SM Nayeem… - New Journal of …, 2019 - pubs.rsc.org
The biomolecular interaction of triamcinolone with bovine serum albumin (BSA) was studied
using various multi-spectroscopic techniques in combination with in silico studies. UV-visible …

Amyloid oligomers, protofibrils and fibrils

MK Siddiqi, N Majid, S Malik, P Alam… - … Protein Complexes II …, 2019 - Springer
Amyloid diseases are of major concern all over the world due to a number of factors
including:(i) aging population,(ii) increasing life span and (iii) lack of effective …

Comprehensive insights into the interactions of dicyclohexyl phthalate and its metabolite to human serum albumin

X Lv, Z Jiang, G Zeng, S Zhao, N Li, F Chen… - Food and Chemical …, 2021 - Elsevier
Phthalate esters (PAEs) are a type of persistent organic pollutants and have received
widespread concerns due to their adverse effects on human health. Dicyclohexyl phthalate …

Probing the binding of phenolic aldehyde vanillin with bovine serum albumin: Evidence from spectroscopic and docking approach

GA Siddiqui, MK Siddiqi, RH Khan, A Naeem - Spectrochimica Acta Part A …, 2018 - Elsevier
The interactions of bovine serum albumin (BSA) with vanillin (VAN) were studied using UV–
vis absorption, fluorescence, synchronous fluorescence, three dimensional fluorescence …

Investigating the site selective binding of busulfan to human serum albumin: Biophysical and molecular docking approaches

M Siddiqi, S Nusrat, P Alam, S Malik… - International journal of …, 2018 - Elsevier
We have studied the binding of busulfan (BN) to human serum albumin (HSA) at
physiological pH 7.4 by using fluorescence, UV–vis and circular dichroism (CD) …

Insight into the binding behavior, structure, and thermal stability properties of β-lactoglobulin/Amoxicillin complex in a neutral environment

S Habibian-Dehkordi, S Farhadian, M Ghasemi… - Food …, 2022 - Elsevier
Antibiotics are extensively used in agriculture and husbandry, thus threatening human
health due to their direct exposure to dairy products. Therefore, it is essential to investigate …