[HTML][HTML] Type 2 inflammation contributes to skin barrier dysfunction in atopic dermatitis

LA Beck, MJ Cork, M Amagai, A De Benedetto… - JID Innovations, 2022 - Elsevier
Skin barrier dysfunction, a defining feature of atopic dermatitis (AD), arises from multiple
interacting systems. In AD, skin inflammation is caused by host–environment interactions …

Revisiting the roles of filaggrin in atopic dermatitis

V Moosbrugger-Martinz, C Leprince… - International Journal of …, 2022 - mdpi.com
The discovery in 2006 that loss-of-function mutations in the filaggrin gene (FLG) cause
ichthyosis vulgaris and can predispose to atopic dermatitis (AD) galvanized the dermatology …

Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis

H He, R Bissonnette, J Wu, A Diaz, ESC Proulx… - Journal of Allergy and …, 2021 - Elsevier
Background Our current understanding of atopic dermatitis (AD) and psoriasis
pathophysiology is largely derived from skin biopsy studies that cause scarring and may be …

Microbiome of the skin and gut in atopic dermatitis (AD): understanding the pathophysiology and finding novel management strategies

JE Kim, HS Kim - Journal of clinical medicine, 2019 - mdpi.com
Atopic dermatitis (AD) is a long-standing inflammatory skin disease that is highly prevalent
worldwide. Multiple factors contribute to AD, with genetics as well as the environment …

The role of the skin microbiome in atopic dermatitis

MR Williams, RL Gallo - Current allergy and asthma reports, 2015 - Springer
Atopic dermatitis (AD) is a common skin disease that affects a large proportion of the
population worldwide. The incidence of AD has increased over the last several decades …

[HTML][HTML] Aging-associated alterations in epidermal function and their clinical significance

Z Wang, MQ Man, T Li, PM Elias, TM Mauro - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Chronologically-aged skin displays multiple functional changes in both the dermis and the
epidermis. It appears that epidermal dysfunction, compromised permeability homeostasis …

Use of tape strips to detect immune and barrier abnormalities in the skin of children with early-onset atopic dermatitis

E Guttman-Yassky, A Diaz, AB Pavel… - JAMA …, 2019 - jamanetwork.com
Importance Molecular profiling of skin biopsies is the criterion standard for evaluating the
cutaneous atopic dermatitis (AD) phenotype. However, skin biopsies are not always feasible …

Tape strips from early‐onset pediatric atopic dermatitis highlight disease abnormalities in nonlesional skin

AB Pavel, Y Renert‐Yuval, J Wu, E Del Duca, A Diaz… - Allergy, 2021 - Wiley Online Library
Background Skin biopsies promote our understanding of atopic dermatitis/AD
pathomechanisms in infants/toddlers with early‐onset AD, but are not feasible in pediatric …

Effect of olive and sunflower seed oil on the adult skin barrier: implications for neonatal skin care

SG Danby, T AlEnezi, A Sultan, T Lavender… - Pediatric …, 2013 - Wiley Online Library
Natural oils are advocated and used throughout the world as part of neonatal skin care, but
there is an absence of evidence to support this practice. The goal of the current study was to …

Skin barrier defects in atopic dermatitis

R Agrawal, JA Woodfolk - Current allergy and asthma reports, 2014 - Springer
Atopic dermatitis (AD) is a chronic inflammatory skin condition with complex etiology that is
dependent upon interactions between the host and the environment. Acute skin lesions …