Animal models of multiple sclerosis: Focus on experimental autoimmune encephalomyelitis

I Bjelobaba, V Begovic‐Kupresanin… - Journal of …, 2018 - Wiley Online Library
Multiple sclerosis (MS) is a chronic, progressive disorder of the central nervous system
(CNS) that affects more than two million people worldwide. Several animal models resemble …

The biochemical and pharmacological properties of ozone: the smell of protection in acute and chronic diseases

R Di Mauro, G Cantarella, R Bernardini… - International journal of …, 2019 - mdpi.com
Ozone therapy has been widely used in everyday clinical practice over the last few years,
leading to significant clinical results in the treatment of herniated discs and pain …

The effects of oxygen–ozone therapy on regulatory T‐cell responses in multiple sclerosis patients

S Tahmasebi, MT Qasim, MV Krivenkova… - Cell biology …, 2021 - Wiley Online Library
Multiple sclerosis (MS) is a common degenerative disorder of the central nervous system.
The decreased frequency and dysfunction of Treg cells cause inflammation and disease …

Ozone-induced neurotoxicity: In vitro and in vivo evidence

A Singh, S Suresh, C Vellapandian - Ageing Research Reviews, 2023 - Elsevier
Together with cities in higher-income nations, it is anticipated that the real global ozone is
rising in densely populated areas of Asia and Africa. This review aims to discuss the …

New insights into the role of oxidative stress mechanisms in the pathophysiology and treatment of multiple sclerosis

B Adamczyk, M Adamczyk-Sowa - Oxidative medicine and …, 2016 - Wiley Online Library
Multiple sclerosis (MS) is a multifactorial disease of the central nervous system (CNS)
characterized by an inflammatory process and demyelination. The etiology of the disease is …

Medical ozone promotes Nrf2 phosphorylation reducing oxidative stress and pro-inflammatory cytokines in multiple sclerosis patients

L Delgado-Roche, M Riera-Romo, F Mesta… - European journal of …, 2017 - Elsevier
Oxidative stress and inflammation play key roles in the pathogenesis of Multiple sclerosis
(MS). Different drugs have been used in the clinical practice, however, there is not a …

Nrf2/HO-1 signaling stimulation through acetyl-11-keto-beta-boswellic acid (AKBA) provides neuroprotection in ethidium bromide-induced experimental model of …

S Upadhayay, S Mehan, A Prajapati, P Sethi, M Suri… - Genes, 2022 - mdpi.com
Multiple sclerosis (MS) is a severe immune-mediated neurological disease characterized by
neuroinflammation, demyelination, and axonal degeneration in the central nervous system …

Paraoxonase role in human neurodegenerative diseases

CO Reichert, D Levy, SP Bydlowski - Antioxidants, 2020 - mdpi.com
The human body has biological redox systems capable of preventing or mitigating the
damage caused by increased oxidative stress throughout life. One of them are the …

Changes in Th17 cells frequency and function after ozone therapy used to treat multiple sclerosis patients

M Izadi, S Tahmasebi, I Pustokhina… - Multiple Sclerosis and …, 2020 - Elsevier
Background: Multiple sclerosis (MS) is a neurodegenerative autoimmune disease with
chronic inflammation. In the course of the disease, the increased levels of Th17 cell, and its …

Serum malondialdehyde as a lipid peroxidation marker in multiple sclerosis patients and its relation to disease characteristics

NAM Ghonimi, KA Elsharkawi, DSM Khyal… - Multiple sclerosis and …, 2021 - Elsevier
Introduction Oxidative stress has been suggested to play a key role in pathogenesis of
multiple sclerosis (MS), but clinical data on oxidative stress markers in MS patients and their …