Machine learning in Alzheimer's disease drug discovery and target identification

C Geng, ZB Wang, Y Tang - Ageing Research Reviews, 2023 - Elsevier
Alzheimer's disease (AD) stands as a formidable neurodegenerative ailment that poses a
substantial threat to the elderly population, with no known curative or disease-slowing drugs …

Neurobiological mechanisms of psychosis in epilepsy: Findings from neuroimaging studies

D Sone - Frontiers in Psychiatry, 2022 - frontiersin.org
Despite the high prevalence and clinical importance of comorbid psychosis in epilepsy, its
neurobiological mechanisms remain understudied. This narrative mini-review aims to …

[HTML][HTML] Performance reserves in brain-imaging-based phenotype prediction

MA Schulz, D Bzdok, S Haufe, JD Haynes, K Ritter - Cell Reports, 2024 - cell.com
This study examines the impact of sample size on predicting cognitive and mental health
phenotypes from brain imaging via machine learning. Our analysis shows a 3-to 9-fold …

A novel automated empirical mode decomposition (EMD) based method and spectral feature extraction for epilepsy EEG signals classification

MG Murariu, FR Dorobanțu, D Tărniceriu - Electronics, 2023 - mdpi.com
The increasing incidence of epilepsy has led to the need for automatic systems that can
provide accurate diagnoses in order to improve the life quality of people suffering from this …

Extending artificial intelligence research in the clinical domain: a theoretical perspective

R Sabharwal, SJ Miah, S Fosso Wamba - Annals of Operations Research, 2022 - Springer
Academic research to the utilization of artificial intelligence (AI) has been proliferated over
the past few years. While AI and its subsets are continuously evolving in the fields of …

Making the invisible visible: advanced neuroimaging techniques in focal epilepsy

D Sone - Frontiers in Neuroscience, 2021 - frontiersin.org
It has been a clinically important, long-standing challenge to accurately localize
epileptogenic focus in drug-resistant focal epilepsy because more intensive intervention to …

An intelligent literature review: adopting inductive approach to define machine learning applications in the clinical domain

R Sabharwal, SJ Miah - Journal of Big Data, 2022 - Springer
Big data analytics utilizes different techniques to transform large volumes of big datasets.
The analytics techniques utilize various computational methods such as Machine Learning …

Impaired functional homotopy and topological properties within the default mode network of children with generalized tonic-clonic seizures: a resting-state fMRI study

Y Li, B Qin, Q Chen, J Chen - Frontiers in Neuroscience, 2022 - frontiersin.org
Introduction The aim of the present study was to examine interhemispheric functional
connectivity (FC) and topological organization within the default-mode network (DMN) in …

Accurate lateralization and classification of MRI-negative 18F-FDG-PET-positive temporal lobe epilepsy using double inversion recovery and machine-learning

I Beheshti, D Sone, N Maikusa, Y Kimura… - Computers in Biology …, 2021 - Elsevier
Objective The main objective of this study was to determine the ability of double inversion
recovery (DIR) data coupled with machine-learning algorithms to distinguish normal …

Convolutional neural network algorithm to determine lateralization of seizure onset in patients with epilepsy: A proof-of-principle study

E Kaestner, J Rao, AJ Chang, ZI Wang, RM Busch… - Neurology, 2023 - AAN Enterprises
Background and Objectives A new frontier in diagnostic radiology is the inclusion of
machine-assisted support tools that facilitate the identification of subtle lesions often not …