Chitooligosaccharides and their biological activities: A comprehensive review

F Liaqat, R Eltem - Carbohydrate polymers, 2018 - Elsevier
Chitin is the most abundant natural polysaccharide and chitosan is its most important
derivative. Regardless of having various bioactivities, the water insolubilities of chitin and …

Biological effects of chitosan and its derivatives

DH Ngo, TS Vo, DN Ngo, KH Kang, JY Je, HND Pham… - Food hydrocolloids, 2015 - Elsevier
Chitosan is a natural nontoxic biopolymer produced by alkaline deacetylation of chitin.
Chitin and chitosan are insoluble in water as well as most organic solvents. Chito-oligomers …

Preparation and biomedical applications of chitin and chitosan nanofibers

K Azuma, S Ifuku, T Osaki, Y Okamoto… - Journal of biomedical …, 2014 - ingentaconnect.com
Chitin (β-(1-4)-poly-N-acetyl-D-glucosamine) is widely distributed in nature and is the
second most abundant polysaccharide after cellulose. Chitin occurs in nature as ordered …

Potential medical applications of chitooligosaccharides

S Anil - Polymers, 2022 - mdpi.com
Chitooligosaccharides, also known as chitosan oligomers or chitooligomers, are made up of
chitosan with a degree of polymerization (DP) that is less than 20 and an average molecular …

Advances in the preparation and assessment of the biological activities of chitosan oligosaccharides with different structural characteristics

J Zhou, B Wen, H Xie, C Zhang, Y Bai, H Cao, Q Che… - Food & Function, 2021 - pubs.rsc.org
Chitosan oligosaccharides (COSs) are widely used biopolymers that have been studied in
relation to a variety of abnormal biological activities in the food and biomedical fields. Since …

N-acetyl-d-glucosamine-based oligosaccharides from chitin: enzymatic production, characterization and biological activities

Y Liu, Z Qin, C Wang, Z Jiang - Carbohydrate Polymers, 2023 - Elsevier
Chitin, the second most abundant biopolymer, possesses diverse applications in the food,
agricultural, and pharmaceutical industries due to its functional properties. However, the …

Chitin and carbon nanotube composites as biocompatible scaffolds for neuron growth

N Singh, J Chen, KK Koziol, KR Hallam, D Janas… - Nanoscale, 2016 - pubs.rsc.org
The design of biocompatible implants for neuron repair/regeneration ideally requires high
cell adhesion as well as good electrical conductivity. Here, we have shown that plasma …

Neuroprotection of andrographolide against microglia-mediated inflammatory injury and oxidative damage in PC12 neurons

Y Xu, D Tang, J Wang, H Wei, J Gao - Neurochemical research, 2019 - Springer
Andrographolide from leaves of Andrographis paniculata has been known to possess
various bioactivities. In the present study, we aimed to explore the neuroprotection of …

The effect of chitin size, shape, source and purification method on immune recognition

FJ Alvarez - Molecules, 2014 - mdpi.com
The animal immune response to chitin is not well understood and needs to be investigated
further. However, this is a challenging topic to study because of the technical difficulties in …

The inhibition of LPS-induced inflammation in RAW264. 7 macrophages via the PI3K/Akt pathway by highly N-acetylated chitooligosaccharide

Q Xu, M Liu, Q Liu, W Wang, Y Du, H Yin - Carbohydrate polymers, 2017 - Elsevier
Chitooligosaccharide (COS) has been shown to regulate many biological functions, such as
antimicrobial effect and antitumor activity. In the present study, highly N-acetylated …