RecQ helicases are an important family of genome surveillance proteins conserved from
bacteria to humans. Each of the five human RecQ helicases plays critical roles in genome …

RecQ helicases are highly conserved from bacteria to man. Germline mutations in three of
the five known family members in humans give rise to debilitating disorders that are …

The RecQ helicases are conserved from bacteria to humans and play a critical role in
genome stability. In humans, loss of RecQ gene function is associated with cancer …

Spinal muscular atrophy (SMA) is a common motor neuron disease that results from
mutations in the Survival of Motor Neuron (SMN) gene. The SMN protein plays a crucial role …

DNA damage repair response is an important biological process involved in maintaining the
fidelity of the genome in eukaryotes and prokaryotes. Several proteins that play a key role in …

The RecQ helicases represent a subfamily of DNA helicases that are highly conserved in
evolution. Loss of RecQ helicase function leads to a breakdown in the maintenance of …

ARIA (Ambiguous Restraints for Iterative Assignment) is a software protocol that integrates
automated nuclear overhanser effect (NOE) assignments into structure calculations. The …

Helicases are molecular motor proteins that couple the hydrolysis of NTP to nucleic acid
unwinding. The growing number of DNA helicases implicated in human disease suggests …

Identification of fungi to the species level has some challenges because of great diversity in
morphology and ecology. Therefore, developing an efficient species recognition system …

ABSTRACT At present, 1.5 million species of fungi are estimated. Among these less than 5%
have been described. Many fungal species cause disease in plants. These diseases cause …