Background Flow diverters are a breakthrough treatment for large and giant intracranial
aneurysms but carry a risk of periprocedural death or major stroke. Pipeline Flex is a second …

OBJECTIVE Flow diversion requires neointimal stent overgrowth to deliver aneurysm
occlusion. The existing literature on aneurysm occlusion is limited by heterogeneous follow …

BACKGROUND The safety and efficacy of the first generation of the Pipeline Embolization
Device (PED; Medtronic Inc) have been proven in large case series. Ischemic events are …

The pathophysiology of giant cerebral aneurysms renders them difficult to treat. Advances in
technology have attempted to address any shortcomings associated with open surgery or …

BACKGROUND Posterior circulation cerebral aneurysms are at higher risk of rupture and
are more symptomatic than those in the anterior circulation. Existing treatments carry …

During intracranial aneurysm embolization with the Pipeline embolization device (PED),
ischemic and hemorrhagic complications have been observed in cases among Western …

BACKGROUND A dramatic improvement in obliteration rates of large, wide-necked
aneurysms has been observed after the FDA approved the Pipeline Embolization Device …

OBJECTIVE Cerebral bypass procedures are microsurgical techniques to augment or
restore cerebral blood flow when treating a number of brain vascular diseases including …

Background Dual antiplatelet therapy (DAT), most commonly with aspirin and Clopidogrel, is
the standard of care for intracranial stenting, including flow diversion. Clopidogrel response …

BACKGROUND Flow diversion has become an accepted endovascular treatment modality
for intracranial aneurysms. Studies comparing different types of flow diverters are currently …