Context Although little is known as yet about the processes that coordinate cell-signalling
pathways, matrix proteins are probably major players in this type of global control. The CCN …

The CCN proteins are key signalling and regulatory molecules involved in many vital
biological functions, including cell proliferation, angiogenesis, tumourigenesis and wound …

Fibulins are a newly recognized family of extracellular matrix proteins. The five known
members of the family share an elongated structure and many calcium-binding sites, owing …

The recent discovery of two structurally related angiogenic inducers, CYR61 and
FISP12/CTGF, has brought to light an emerging family of conserved and modular proteins …

Connective Tissue Growth Factor/Cysteine- Rich 61/Nephroblastoma Overexpressed (CCN)
Family* | Endocrine Reviews | Oxford Academic Skip to Main Content Advertisement Oxford …

We have performed a screening analysis of differential gene expression using a defined in
vitro model of human capillary tube formation. Gene array, differential display and cDNA …

Connective tissue growth factor (CTGF) stimulatesin vitrofibroblast proliferation and
extracellular matrix synthesis. The aim of this study was to assess the role of CTGF in liver …

The CCN family of genes presently consists of six distinct members encoding proteins that
participate in fundamental biological processes such as cell proliferation, attachment …

Connective tissue growth factor (CCN2, also known as CTGF) is a matricellular protein that
appears to play an important role in hepatic stellate cell (HSC)-mediated fibrogenesis. After …

Cysteine-rich 61 (Cyr61, CCN1) and connective tissue growth factor (CTGF, CCN2) are
growth factor–inducible immediate-early gene products found in blood vessel walls and …