The search for neuroimaging and cognitive endophenotypes: a critical systematic review of studies involving unaffected first-degree relatives of individuals with bipolar …

KW Miskowiak, HL Kjaerstad, I Meluken… - Neuroscience & …, 2017 - Elsevier
The phenomenology and underlying pathophysiology of bipolar disorder (BD) are
heterogeneous. The identification of putative endophenotypes for BD can aid in the …

A review of resting-state fMRI correlations with executive functions and social cognition in bipolar disorder

Y Massalha, E Maggioni, A Callari, P Brambilla… - Journal of Affective …, 2023 - Elsevier
Background Deficits in executive functions (EF) and social cognition (SC) are often observed
in bipolar disorder (BD), leading to a severe impairment in engaging a functional interaction …

Aberrant cognition in newly diagnosed patients with bipolar disorder and their unaffected relatives

HL Kjærstad, N Mistarz, K Coello, S Stanislaus… - Psychological …, 2020 - cambridge.org
BackgroundPatients with bipolar disorder (BD) experience persistent impairments in both
affective and non-affective cognitive function, which is associated with a worse course of …

Aberrant functional connectivity of sensorimotor network and its relationship with executive dysfunction in bipolar disorder type I

W Zhu, W Tang, Y Liang, X Jiang, Y Li… - Frontiers in …, 2022 - frontiersin.org
Background The key pathophysiological mechanism of executive dysfunction in patients
with bipolar disorder type I (BD-I) is still unclear. Previous studies have demonstrated that it …

Associations between executive function impairment and biochemical abnormalities in bipolar disorder with suicidal ideation

S Zhong, Y Wang, S Lai, T Liu, X Liao, G Chen… - Journal of Affective …, 2018 - Elsevier
Background Executive dysfunction and biochemical abnormalities using proton magnetic
resonance spectroscopy (1 H-MRS) have been reported in bipolar disorder (BD). Much less …

Applying dimensional psychopathology: Transdiagnostic prediction of executive cognition using brain connectivity and inflammatory biomarkers

Y Wei, FY Womer, K Sun, Y Zhu, D Sun… - Psychological …, 2023 - cambridge.org
Background The association between executive dysfunction, brain dysconnectivity, and
inflammation is a prominent feature across major psychiatric disorders (MPDs) …

[HTML][HTML] Is processing speed a valid neurocognitive endophenotype in bipolar disorder? Evidence from a longitudinal, family study

SC Luperdi, P Correa-Ghisays, J Vila-Francés… - Journal of Psychiatric …, 2021 - Elsevier
Background Substantial evidence supports the existence of neurocognitive endophenotypes
in bipolar disorder (BD), but very few longitudinal studies have included unaffected relatives …

Disturbances of dynamic function in patients with bipolar disorder I and its relationship with executive-function deficit

Y Liang, X Jiang, W Zhu, Y Shen, F Xue, Y Li… - Frontiers in …, 2020 - frontiersin.org
Abnormity in brain regional function and inter-regional cooperation have been linked with
the dysfunction during cognitive and emotional processing in bipolar disorder (BD) patients …

ANK3 gene polymorphism Rs10994336 influences executive functions by modulating methylation in patients with bipolar disorder

L Tang, J Liu, Y Zhu, J Duan, Y Chen, Y Wei… - Frontiers in …, 2021 - frontiersin.org
Background: A large body of evidence suggests that epigenetic modification including DNA
methylation plays a critical role in BD's pathogenesis while the identification of methylation …

Visual memory dysfunction as a neurocognitive endophenotype in bipolar disorder patients and their unaffected relatives. Evidence from a 5-year follow-up Valencia …

P Correa-Ghisays, JV Sánchez-Ortí… - Journal of Affective …, 2019 - Elsevier
Background Scarce research has focused on Visual Memory (VM) deficits as a possible
neurocognitive endophenotype of bipolar disorder (BD). The main aim of this longitudinal …