Effects of adolescent alcohol consumption on the brain and behaviour

LP Spear - Nature Reviews Neuroscience, 2018 - nature.com
Per occasion, alcohol consumption is higher in adolescents than in adults in both humans
and laboratory animals, with changes in the adolescent brain probably contributing to this …

What motivates adolescents? Neural responses to rewards and their influence on adolescents' risk taking, learning, and cognitive control

ACK Van Duijvenvoorde, S Peters, BR Braams… - Neuroscience & …, 2016 - Elsevier
Adolescence is characterized by pronounced changes in motivated behavior, during which
emphasis on potential rewards may result in an increased tendency to approach things that …

[HTML][HTML] Adolescent substance use and the brain: behavioral, cognitive and neuroimaging correlates

S Hamidullah, HHA Thorpe, JA Frie… - Frontiers in Human …, 2020 - frontiersin.org
Adolescence is an important ontogenetic period that is characterized by behaviors such as
enhanced novelty-seeking, impulsivity, and reward preference, which can give rise to an …

Unraveling age, puberty and testosterone effects on subcortical brain development across adolescence

LM Wierenga, MGN Bos, E Schreuders… - …, 2018 - Elsevier
The onset of adolescence in humans is marked by hormonal changes that give rise to
secondary sexual characteristics, noted as puberty. It has, however, proven challenging to …

Orbitofrontal circuits control multiple reinforcement-learning processes

SM Groman, C Keistler, AJ Keip, E Hammarlund… - Neuron, 2019 - cell.com
Adaptive decision making in dynamic environments requires multiple reinforcement-learning
steps that may be implemented by dissociable neural circuits. Here, we used a novel …

A three‐wave longitudinal study of subcortical–cortical resting‐state connectivity in adolescence: Testing age‐and puberty‐related changes

ACK Van Duijvenvoorde, B Westhoff… - Human brain …, 2019 - Wiley Online Library
Adolescence is the transitional period between childhood and adulthood, characterized by
substantial changes in reward‐driven behavior. Although reward‐driven behavior is …

[HTML][HTML] Genetic and environmental influences on functional connectivity within and between canonical cortical resting-state networks throughout adolescent …

J Teeuw, RM Brouwer, JP Guimarães, P Brandner… - NeuroImage, 2019 - Elsevier
The human brain is active during rest and hierarchically organized into intrinsic functional
networks. These functional networks are largely established early in development, with …

The role of the orbitofrontal cortex in alcohol use, abuse, and dependence

DE Moorman - Progress in Neuro-Psychopharmacology and …, 2018 - Elsevier
One of the major functions of the orbitofrontal cortex (OFC) is to promote flexible motivated
behavior. It is no surprise, therefore, that recent work has demonstrated a prominent impact …

[HTML][HTML] Effects of ambient fine particulates, nitrogen dioxide, and ozone on maturation of functional brain networks across early adolescence

DL Cotter, CE Campbell, K Sukumaran… - Environment …, 2023 - Elsevier
Background Air pollution is linked to neurodevelopmental delays, but its association with
longitudinal changes in brain network development has yet to be investigated. We aimed to …

Exogenous ghrelin administration increases alcohol self-administration and modulates brain functional activity in heavy-drinking alcohol-dependent individuals

M Farokhnia, EN Grodin, MR Lee, EN Oot… - Molecular …, 2018 - nature.com
Preclinical evidence suggests that ghrelin, a peptide synthesized by endocrine cells of the
stomach and a key component of the gut–brain axis, is involved in alcohol seeking as it …