Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …

Over the last decades, the concept of precision medicine has dramatically renewed the field
of medical oncology; the introduction of patient-tailored therapies has significantly improved …

Cancer biomarkers have transformed current practices in the oncology clinic. Continued
discovery and validation are crucial for improving early diagnosis, risk stratification, and …

Background Set comparisons permeate a large number of data analysis workflows, in
particular workflows in biological sciences. Venn diagrams are frequently employed for such …

Nowadays, proteomic studies no longer focus only on identifying as many proteins as
possible in a given sample, but aiming for an accurate quantification of them. Especially in …

Molecular biomarkers hold promise to advance the noninvasive diagnosis of male
reproductive system disorders and facilitate the identification and management of these …

Prostate cancer is the second most frequently diagnosed non-skin cancer in men worldwide.
Patient outcomes are remarkably heterogeneous and the best existing clinical prognostic …

Extracellular vesicles (EVs) are released by nearly all cell types as part of normal cell
physiology, transporting biological cargo, including nucleic acids and proteins, across the …

Expressed prostatic secretions (EPS) are proximal fluids of the prostate that are increasingly
being utilized as a clinical source for diagnostic and prognostic assays for prostate cancer …

Background Cancer cells are able to change the protein expression and behavior of non-
cancerous surrounding cells. Exosomes, secreted by prostate cancer (PCa) cells, may have …