Malaria is a devastating infectious disease that is caused by blood-borne apicomplexan
parasites of the genus Plasmodium. These pathogens have a complex lifecycle, which …

Certain kinetoplastid (Leishmania spp. and Trypanosoma cruzi) and apicomplexan
parasites (Plasmodium falciparum and Toxoplasma gondii) are capable of invading human …

Nucleosome assembly proteins (NAPs) are histone chaperones that play a central role in
facilitating chromatin assembly/disassembly which is of fundamental importance for DNA …

Due to the unique selective pressures and extreme changes faced by the human malaria
parasite Plasmodium falciparum throughout its life cycle, the parasite has evolved distinct …

Human FACT (facilitates chromatin transcription) consists of the proteins SPT16 and SSRP1
and acts as a histone chaperone in the (dis) assembly of nucleosome (and thereby …

The dynamic chromatin landscape displaying combinatorial complexity of the epigenome
impacts gene expression that underlies many events of differentiation and cell cycle …

Faster reinduction of heat acclimation (AC) after its decline indicates “AC memory.” Our
previous results revealed involvement of epigenetic mechanisms of transcriptional …

Membrane microdomains that include lipid rafts, are involved in key physiological and
pathological processes and participate in the entry of endocellular pathogens. These …

Epigenetic modifications have emerged as critical regulators of virulence genes and stage-
specific gene expression in Plasmodium falciparum. However, the specific roles of histone …

Plasmodium mature sexual cycle occurs in the vector mosquitoes and ensures the
transmission to a new host. Gametogenesis takes place within minutes in the vector midgut …