Pathogenicity and virulence of the liver flukes Fasciola hepatica and Fasciola Gigantica that cause the zoonosis Fasciolosis

R Lalor, K Cwiklinski, NED Calvani, A Dorey, S Hamon… - Virulence, 2021 - Taylor & Francis
Fasciolosis caused by the liver flukes Fasciola hepatica and Fasciola gigantica is one of the
most important neglected parasitic diseases of humans and animals. The ability of the …

Immunomodulation by helminths: intracellular pathways and extracellular vesicles

A Zakeri, EP Hansen, SD Andersen… - Frontiers in …, 2018 - frontiersin.org
Helminth parasites are masters at manipulating host immune responses, using an array of
sophisticated mechanisms. One of the major mechanisms enabling helminths to establish …

Fasciola hepatica-Derived Molecules as Regulators of the Host Immune Response

S Ryan, J Shiels, CC Taggart, JP Dalton… - Frontiers in …, 2020 - frontiersin.org
Helminths (worms) are one of the most successful organisms in nature given their ability to
infect millions of humans and animals worldwide. Their success can be attributed to their …

Recent progress in the development of liver fluke and blood fluke vaccines

DP McManus - Vaccines, 2020 - mdpi.com
Liver flukes (Fasciola spp., Opisthorchis spp., Clonorchis sinensis) and blood flukes
(Schistosoma spp.) are parasitic helminths causing neglected tropical diseases that result in …

Helminth glycomics–glycan repertoires and host-parasite interactions

CH Hokke, A van Diepen - Molecular and Biochemical Parasitology, 2017 - Elsevier
Glycoproteins and glycolipids of parasitic helminths play important roles in biology and host-
parasite interaction. This review discusses recent helminth glycomics studies that have been …

Advances in Fasciola hepatica research using 'omics' technologies

K Cwiklinski, JP Dalton - International journal for parasitology, 2018 - Elsevier
The liver fluke Fasciola hepatica is an economically important pathogen of livestock
worldwide, as well as being an important neglected zoonosis. Parasite control is reliant on …

Fasciola hepatica Infection in Cattle: Analyzing Responses of Peripheral Blood Mononuclear Cells (PBMC) Using a Transcriptomics Approach

A Garcia-Campos, CN Correia… - Frontiers in …, 2019 - frontiersin.org
The parasitic helminth Fasciola hepatica (liver fluke) causes economic loss to the livestock
industry globally and also causes zoonotic disease. New control strategies such as vaccines …

Fasciola hepatica glycoconjugates immuneregulate dendritic cells through the Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin …

E Rodríguez, H Kalay, V Noya, N Brossard… - Scientific reports, 2017 - nature.com
Dendritic cell-specific ICAM-3 grabbing non-integrin (DC-SIGN) expressed on a variety of
DCs, is a C-type lectin receptor that recognizes glycans on a diverse range of pathogens …

Human hydatid cyst fluid-induced therapeutic anti-cancer immune responses via NK1.1+ cell activation in mice

E Berriel, T Freire, C Chiale, E Rodríguez… - Cancer Immunology …, 2021 - Springer
Echinococcus granulosus is a cestode parasite which causes cystic echinococcosis
disease. Previously we observed that vaccination with E. granulosus antigens from human …

An Update on the Pathogenesis of Fascioliasis: What Do We Know?

MB Tanabe, MA Caravedo… - … and Reports in …, 2024 - Taylor & Francis
Fasciola hepatica is a trematode parasite distributed worldwide. It is known to cause disease
in mammals, producing significant economic loses to livestock industry and burden to …