The amphibian's spleen as a source of biomarkers for ecotoxicity assessment: Historical review and trends

E Tsukada, CC Rodrigues, JC Jacintho… - Science of The Total …, 2023 - Elsevier
Amphibians are very sensitive to many environmental changes, so these animals are
considered good bioindicator models for ecotoxicology. Given the importance of the …

Hematopoietic stem and progenitor cells (HSPCs)

K Bujko, M Kucia, J Ratajczak, MZ Ratajczak - Stem cells: therapeutic …, 2019 - Springer
Hematopoietic stem/progenitor cells (HSPCs) isolated from bone marrow have been
successfully employed for 50 years in hematological transplantations. Currently, these cells …

Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche

FG Kapp, JR Perlin, EJ Hagedorn, JM Gansner… - Nature, 2018 - nature.com
Haematopoietic stem and progenitor cells (HSPCs) require a specific microenvironment, the
haematopoietic niche, which regulates HSPC behaviour,. The location of this niche varies …

Biology of amphibian granulocytes-From evolutionary pressures to functional consequences

KA Hauser, CN Garvey, M Popovic, L Grayfer - … & Comparative Immunology, 2023 - Elsevier
Granulocyte-lineage cells are important innate immune effectors across all vertebrates.
Named for conspicuous secretory granules, granulocytes have historically been studied for …

Amphibian macrophage development and antiviral defenses

L Grayfer, J Robert - Developmental & Comparative Immunology, 2016 - Elsevier
Macrophage lineage cells represent the cornerstone of vertebrate physiology and immune
defenses. In turn, comparative studies using non-mammalian animal models have revealed …

Integrating morphology and physiology of the key endocrine organ during tadpole development: the interrenal gland

E Regueira, MEA O'Donohoe… - Journal of …, 2022 - Wiley Online Library
Indirect development is widespread in anurans and is considered an ancestral condition.
The metamorphosis of larvae into juveniles involves highly coordinated morphological …

In-silico analysis of myeloid cells across the animal kingdom reveals neutrophil evolution by colony-stimulating factors

D Pinheiro, MA Mawhin, M Prendecki, KJ Woollard - Elife, 2020 - elifesciences.org
Neutrophils constitute the largest population of phagocytic granulocytes in the blood of
mammals. The development and function of neutrophils and monocytes is primarily …

Amphibian myelopoiesis

A Yaparla, DB Stern, MRH Hossainey… - Developmental & …, 2023 - Elsevier
Macrophage-lineage cells are indispensable to immunity and physiology of all vertebrates.
Amongst these, amphibians represent a key stage in vertebrate evolution and are facing …

Immune-pineal-ocular Axis in Amphibians: Unveiling A Novel Connection

SCM Titon, PGG Neto, B Titon Jr… - Integrative and …, 2024 - academic.oup.com
Melatonin is a hormone known as an endogenous temporal marker signaling the dark
phase of the day. Although the eyes seem to be the main site of melatonin production in …

Diverse of erythropoiesis responding to hypoxia and low environmental temperature in vertebrates

S Maekawa, T Kato - BioMed Research International, 2015 - Wiley Online Library
Erythrocytes are responsible for transporting oxygen to tissue and are essential for the
survival of almost all vertebrate animals. Circulating erythrocyte counts are tightly regulated …