Natural products can generally exhibit a variety of biological activities, but most show
mediocre performance in preliminary activity evaluation. Natural products often require …

Abstract β-Carboline alkaloids are an eminent class of nitrogen-based natural alkaloids and
therapeutic molecules which exert various pharmacological activities through diverse …

Malaria remains one of the major health problems worldwide. The lack of an effective
vaccine and the increasing resistance of Plasmodium to the approved antimalarial drugs …

Cancer and malaria are both global health threats. Due to the increase in the resistance to
the known drugs, research on new active substances is a priority. Here, we present the …

Malaria is still one of the major killer parasitic diseases in tropical settings, posing a public
health threat. The development of antimalarial drug resistance is reversing the gains made …

Inhibiting quorum sensing (QS), a central communication system, is a promising strategy to
combat bacterial pathogens without antibiotics. Here, we designed novel hybrid compounds …

The rise of the resistance of the malaria parasite to the currently approved therapy urges the
discovery and development of new efficient agents. Previously we have demonstrated that …

Malaria, one of the oldest parasitic diseases, remains a global health threat, and the
increasing resistance of the malaria parasite to current antimalarials is forcing the discovery …

As cancer remains one of the major health burdens worldwide, novel agents, due to the
development of resistance, are needed. In this work, we designed and synthesized …

A 1, 3-dihexadecyl-1 H-benzo [d] imidazol-3-ium-tetraphenylborate (DHBI-TPB) ion-pair
implemented in DHBI-TPB surfactant sensor was used for the potentiometric quantification of …