Acute pain signaling has a key protective role and is highly evolutionarily conserved.
Chronic pain, however, is maladaptive, occurring as a consequence of injury and disease …

Purpose Diabetic peripheral neuropathy (DPN) is the commonest cause of neuropathy
worldwide, and its prevalence increases with the duration of diabetes. It affects …

In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …

Corneal nerves are responsible for the sensations of touch, pain, and temperature and play
an important role in the blink reflex, wound healing, and tear production and secretion …

Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers,
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …

Background/Aims Long COVID is characterised by a range of potentially debilitating
symptoms which develop in at least 10% of people who have recovered from acute SARS …

Neurotrophic keratitis (NK) is a degenerative corneal disease caused by damage of
trigeminal corneal innervation, which leads to spontaneous epithelial breakdown and …

OBJECTIVE To assess the diagnostic utility of corneal confocal microscopy (CCM) for
diabetic peripheral neuropathy (DPN) and the risk factors for corneal nerve loss …

Diabetic peripheral neuropathy (DPN) is the most common complication of both type 1 and 2
diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations …

OBJECTIVE The accurate quantification of human diabetic neuropathy is important to define
at-risk patients, anticipate deterioration, and assess new therapies. RESEARCH DESIGN …