Profiling genome-wide DNA methylation
DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …
gene expression and therefore a broad range of biological processes and diseases. DNA …
DNA methylation data by sequencing: experimental approaches and recommendations for tools and pipelines for data analysis
I Rauluseviciute, F Drabløs, MB Rye - Clinical epigenetics, 2019 - Springer
Sequencing technologies have changed not only our approaches to classical genetics, but
also the field of epigenetics. Specific methods allow scientists to identify novel genome-wide …
also the field of epigenetics. Specific methods allow scientists to identify novel genome-wide …
CGmapTools improves the precision of heterozygous SNV calls and supports allele-specific methylation detection and visualization in bisulfite-sequencing data
Motivation DNA methylation is important for gene silencing and imprinting in both plants and
animals. Recent advances in bisulfite sequencing allow detection of single nucleotide …
animals. Recent advances in bisulfite sequencing allow detection of single nucleotide …
circlncRNAnet: an integrated web-based resource for mapping functional networks of long or circular forms of noncoding RNAs
Background Despite their lack of protein-coding potential, long noncoding RNAs (lncRNAs)
and circular RNAs (circRNAs) have emerged as key determinants in gene regulation, acting …
and circular RNAs (circRNAs) have emerged as key determinants in gene regulation, acting …
Challenges and perspectives in the epigenetics of climate change-induced forests decline
I García-García, B Méndez-Cea… - Frontiers in Plant …, 2022 - frontiersin.org
Forest tree species are highly vulnerable to the effects of climate change. As sessile
organisms with long generation times, their adaptation to a local changing environment may …
organisms with long generation times, their adaptation to a local changing environment may …
Early microbial colonization affects DNA methylation of genes related to intestinal immunity and metabolism in preterm pigs
Epigenetic regulation may play an important role in mediating microbe–host interactions and
adaptation of intestinal gene expression to bacterial colonization just after birth. This is …
adaptation of intestinal gene expression to bacterial colonization just after birth. This is …
Bicycle: a bioinformatics pipeline to analyze bisulfite sequencing data
O Graña, H López-Fernández, F Fdez-Riverola… - …, 2018 - academic.oup.com
High-throughput sequencing of bisulfite-converted DNA is a technique used to measure
DNA methylation levels. Although a considerable number of computational pipelines have …
DNA methylation levels. Although a considerable number of computational pipelines have …
Tumor purity and differential methylation in cancer epigenomics
F Wang, N Zhang, J Wang, H Wu… - Briefings in functional …, 2016 - academic.oup.com
DNA methylation is an epigenetic modification of DNA molecule that plays a vital role in
gene expression regulation. It is not only involved in many basic biological processes, but …
gene expression regulation. It is not only involved in many basic biological processes, but …
Integrating DNA methylation and hydroxymethylation data with the mint pipeline
DNA methylation (5mC) plays important roles in mammalian development, oncogenesis,
treatment response, and responses to the environment. DNA hydroxymethylation (5hmC) is …
treatment response, and responses to the environment. DNA hydroxymethylation (5hmC) is …
[HTML][HTML] Uncovering Alterations in Cancer Epigenetics via Trans-Dimensional Markov Chain Monte Carlo and Hidden Markov Models
F Shokoohi, SH Khaniki - bioRxiv, 2023 - ncbi.nlm.nih.gov
Epigenetic alterations are key drivers in the development and progression of cancer.
Identifying differentially methylated cytosines (DMCs) in cancer samples is a crucial step …
Identifying differentially methylated cytosines (DMCs) in cancer samples is a crucial step …