WG Land, P Agostinis, S Gasser, AD Garg… - American Journal of …, 2016 - Elsevier
Upon solid organ transplantation and during cancer immunotherapy, cellular stress responses result in the release of damage-associated molecular patterns (DAMPs). The …
E Wojtaszek, U Oldakowska-Jedynak… - oxidative medicine …, 2021 - Wiley Online Library
Patients with chronic kidney disease (CKD) are at a high risk for cardiovascular disease (CVD), and approximately half of all deaths among patients with CKD are a direct result of …
WG Land - Transplantation, 2005 - journals.lww.com
Abstract The Injury Hypothesis, first published in 1994 and modified several times between 1996 and 2002, holds that the reactive oxygen species-mediated reperfusion injury to …
Maintaining organ viability after donation until transplantation is critically important for optimal graft function and survival. To date, static cold storage is the most widely used form …
Y Chen, J Shi, TC Xia, R Xu, X He… - Cell …, 2019 - journals.sagepub.com
Solid organ transplantation was one of the greatest medical advances during the past few decades. Organ preservation solutions have been applied to diminish ischemic/hypoxic …
N Serkova, TF Fuller, J Klawitter, CE Freise… - Kidney international, 2005 - Elsevier
1 H-NMR–based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants. Background Severe ischemia/reperfusion (IR) injury is a risk factor for …
Hypothermic perfusion preservation (HPP) was an integral step in the development of early clinical transplantation programmes, and considerable progress was made in understanding …
J De Beule, I Jochmans - Journal of Clinical Medicine, 2020 - mdpi.com
The final decision to accept an organ for transplantation remains a subjective one. With “poor organ quality” commonly cited as a major reason for kidney discard, accurate …
C Dictus, B Vienenkoetter… - Clinical …, 2009 - Wiley Online Library
Caring for a brain dead potential organ donor requires a shift in critical care from the extensive treatment of increased intracranial pressure towards strategies to maintain donor …