Hypocretin as a hub for arousal and motivation
The lateral hypothalamus is comprised of a heterogeneous mix of neurons that serve to
integrate and regulate sleep, feeding, stress, energy balance, reward, and motivated …
integrate and regulate sleep, feeding, stress, energy balance, reward, and motivated …
Sleep and memory: The impact of sleep deprivation on transcription, translational control, and protein synthesis in the brain
LC Lyons, Y Vanrobaeys, T Abel - Journal of neurochemistry, 2023 - Wiley Online Library
In countries around the world, sleep deprivation represents a widespread problem affecting
school‐age children, teenagers, and adults. Acute sleep deprivation and more chronic sleep …
school‐age children, teenagers, and adults. Acute sleep deprivation and more chronic sleep …
Sleep, synaptic homeostasis and neuronal firing rates
C Cirelli - Current opinion in neurobiology, 2017 - Elsevier
Highlights•In mouse cortex sleep is associated with broad but selective synaptic
downscaling.•Acute sleep loss negatively impacts synapses in CA1 more than in …
downscaling.•Acute sleep loss negatively impacts synapses in CA1 more than in …
International union of basic and clinical pharmacology CXIV: Orexin receptor function, nomenclature and pharmacology
The orexin system consists of the peptide transmitters orexin-A and-B and the G protein-
coupled orexin receptors OX 1 and OX 2. Orexin receptors are capable of coupling to all four …
coupled orexin receptors OX 1 and OX 2. Orexin receptors are capable of coupling to all four …
Heterogeneity of hypocretin/orexin neurons
D Sagi, L de Lecea, L Appelbaum - … System. Basic Science and Role in …, 2021 - karger.com
The multifunctional, hypothalamic hypocretin/orexin (HCRT)-producing neurons regulate an
array of physiological and behavioral states including arousal, sleep, feeding, emotions …
array of physiological and behavioral states including arousal, sleep, feeding, emotions …
Neuronal and molecular mechanisms of sleep homeostasis
JM Donlea - Current opinion in insect science, 2017 - Elsevier
Highlights•dFB and EB R2 neurons detect homeostatic changes in sleep need and induce
recovery sleep.•Memory-encoding MB circuits require sleep to form new …
recovery sleep.•Memory-encoding MB circuits require sleep to form new …
Sleep loss and structural plasticity
CC Areal, SC Warby, V Mongrain - Current opinion in neurobiology, 2017 - Elsevier
Highlights•Acute sleep loss modifies synaptic structure in a region-dependent
manner.•Sleep loss mostly reduces dendritic spine number in the mammalian …
manner.•Sleep loss mostly reduces dendritic spine number in the mammalian …
Dietary intake of polyunsaturated fatty acids alleviates cognition deficits and depression-like behaviour via cannabinoid system in sleep deprivation rats
T Wang, K Niu, A Fan, N Bi, H Tao, XT Chen… - Behavioural brain …, 2020 - Elsevier
Sleep deprivation (SD) is a common feature in modern society. Prolonged sleep deprivation
causes cognition deficits and depression-like behavior in the model of animal experiments …
causes cognition deficits and depression-like behavior in the model of animal experiments …
Modeling sleep and neuropsychiatric disorders in zebrafish
T Levitas-Djerbi, L Appelbaum - Current opinion in neurobiology, 2017 - Elsevier
Highlights•Sleep is conserved in zebrafish and defined by behavioral criteria.•Zebrafish
enable imaging of single organelles and cells during the day and night.•Genetic and …
enable imaging of single organelles and cells during the day and night.•Genetic and …
[PDF][PDF] Oxford research encyclopedia of neuroscience
R Shapley - 2019 - cns.nyu.edu
Color perception in macaque monkeys and humans depends on the visually evoked activity
in three cone photoreceptors and on neuronal post-processing of cone signals. Neuronal …
in three cone photoreceptors and on neuronal post-processing of cone signals. Neuronal …