Citicoline is the generic name of the pharmaceutical substance that chemically is cytidine-
5′-diphosphocholine (CDP-choline), which is identical to the natural intracellular precursor …

This review is based on the previous one published in 2010–Secades JJ. Citicoline:
pharmacological and clinical review, 2010 update. Rev Neurol 2011; 52 (Suppl 2): S1-62 …

Cytidine 5'-diphosphocholine, CDP-choline, or citicoline is an essential intermediate in the
biosynthetic pathway of structural phospholipids in cell membranes, particularly …

This review is based on the previous one published in 2010–Secades JJ. Citicoline:
pharmacological and clinical review, 2010 update. Rev Neurol 2011; 52 (Suppl 2): S1-62 …

Phosphatidylcholine (PtdCho) is a major membrane phospholipid, and its loss is sufficient in
itself to induce cell death. PtdCho homeostasis is regulated by the balance between …

Introduction There is a lack of robust metabolic imaging techniques that can be routinely
applied to characterize lesions in patients with brain tumors. Here we explore in an animal …

Vascular cognitive impairment is a process which is more frequent in patients with
cardiovascular risk factors. The etiology of this kind of impairment could be related to …

Intraperitoneal administration of CDP-choline (200–900 μmol/kg) increased blood pressure
and decreased heart rate of rats in a dose-and time-dependent manner. These responses …

AIM: The aim of this study was to investigate the dose dependence of citicoline's previously-
reported effects on recovery of peripheral nerve injury. MATERIAL and METHODS: Right …

Citicoline (cytidine-5′-diphosphocholine or CDP-choline) is a precursor essential for the
synthesis of phosphatidylcholine, one of the cell membrane components that is degraded …