Abstract Cisplatin or (SP-4-2)-diamminedichloridoplatinum (II) is one of the most potential
and widely used drugs for the treatment of various solid cancers such as testicular, ovarian …

Cisplatin, cisplatinum, or cis-diamminedichloroplatinum (II), is a well-known
chemotherapeutic drug. It has been used for treatment of numerous human cancers …

Melittin (MEL), a major peptide component of bee venom, is an attractive candidate for
cancer therapy. This agent has shown a variety of anti-cancer effects in preclinical cell …

Melittin, the main venom component of the European Honeybee, is a cationic linear peptide-
amide of 26 amino acid residues with the sequence: GIGAVLKVLTTGLPALISWIKRKRQQ …

Bee venom (BV) is a rich source of secondary metabolites from honeybees (Apis mellifera
L.). It contains a variety of bioactive ingredients including peptides, proteins, enzymes, and …

Bee venom (BV) or apitoxin is a complex mixture of substances with reported biological
activity. In the present work, five bee venom samples obtained from Apis mellifera iberiensis …

Bee venom and its main constituent melittin (MEL) have been extensively studied in the
treatment of tumors. However, the non-specific cytotoxicity and hemolytic activity have …

Melittin (MEL), a small peptide component of bee venom, has been reported to exhibit anti-
cancer effects in vitro and in vivo. However, its clinical applicability is disputed because of its …

Cisplatin is a known antitumor drug, but its mechanisms of action are not fully elucidated. In
this research, we studied the anticancer potential of cisplatin at doses of 1, 2, or 3 μM using …

Cancer represents the disease of the millennium, a major problem in public health. The
proliferation of tumor cells, angiogenesis, and the relationship between the cancer cells and …