The dark side of platinum based cytostatic drugs: From detection to removal

Y Roque-Diaz, M Sanadar, D Han, M López-Mesas… - Processes, 2021 - mdpi.com
The uncontrolled release of pharmaceutical drugs into the environment raised serious
concerns in the last decades as they can potentially exert adverse effects on living …

[HTML][HTML] Synthesis, structural study and antitumor activity of novel alditol-based imidazophenanthrolines (aldo-IPs)

A Gómez-Bra, L Gude, MS Arias-Pérez - Bioorganic & Medicinal Chemistry, 2024 - Elsevier
A series of 1H-imidazo [4, 5-f][1, 10] phenanthroline derivatives functionalized at 2-position
with chiral, and conformationally flexible polyhydroxy alkyl chains derived from …

[HTML][HTML] 1H-imidazo [4, 5-f][1, 10] phenanthroline carbohydrate conjugates: Synthesis, DNA interactions and cytotoxic activity

P Gratal, MS Arias-Perez, L Gude - Bioorganic Chemistry, 2022 - Elsevier
Here we present a novel family of carbohydrate conjugates based on the 2-aryl-imidazo [4, 5-
f][1, 10] phenanthroline core modified with carbohydrates (carb-APIPs). The hybrid …

L-tetrahydropalmatine attenuates cisplatin-induced nephrotoxicity via selective inhibition of organic cation transporter 2 without impairing its antitumor efficacy

C Li, L Li, Y Yi, W Wang, J Yuan, F Tan, D Fang… - Biochemical …, 2020 - Elsevier
Cisplatin is a first-line chemotherapeutic agent that is widely used for treatment of various
solid tumors. However, cisplatin-induced adverse effects, particularly severe nephrotoxicity …

Anticancer property of lanthanide sulfate nanostructure against neuroblastoma-neuro2a cell line

M Haghighat, A Naroie, A Rezvani, M Hakimi… - BioNanoScience, 2021 - Springer
A novel lanthanum (III) complex with 8-Hq= 8-hydroxy quinoline and phen-dione= 1, 10-
phenanthroline-5, 6-dione was synthesized using the reflux method. The complex was …

Structural characterization and antileishmanial activity of newly synthesized organo-bismuth (V) carboxylates: experimental and molecular docking studies

S Andleeb, MK Rauf, SS Azam, I Haq, MN Tahir… - JBIC Journal of …, 2022 - Springer
In a quest to discover new formulations for the treatment of various parasitic diseases, a
series of heteroleptic triorganobismuth (V) biscarboxylates of type [BiR3 (O2CR′) 2], where …

Selenocysteine of thioredoxin reductase as the primary target for the antitumor metallodrugs: A computational point of view

I Tolbatov, A Marrone - Journal of Organometallic Chemistry, 2022 - Elsevier
Selenocysteine (Sec) has been recognized as a soft metal-coordinating residue that dues its
relevance to the important role played in the catalytic activity of thioredoxin reductase (TrxR) …

Quantum mechanical approaches and molecular docking analysis of platinum metal-based anticancer drugs Lobaplatin and Heptaplatin targeting cancer DNA-a …

M Sahadevan, M Sundaram, K Subramanian - Chemical Physics Letters, 2024 - Elsevier
The structural analysis and chemical reactivity of Lobaplatin and Heptaplatin were done
using Spectral analysis, NBO analysis, and Global Chemical Reactivity and HOMO-LUMO …

RETRACTED ARTICLE: Two new Bi (III) and Ce (III) chelates incorporating 1, 10-phenanthroline-2, 9-dicarboxylic acid: structure elucidation and anti-lung cancer …

D Li, LF Li, ZF Zhang, WB Shi, L Pan… - Inorganic and Nano …, 2020 - Taylor & Francis
Abstract We, the Editors and Publisher of the journal Inorganic and Nano-Metal Chemistry,
have retracted the following article: Di Li, Li-Fei Li, Zhi-Fang Zhang, Wen-Bo Shi, Lei Pan & …

[PDF][PDF] Complejos metálicos basados en macrociclos de éteres corona. análisis de reactividad, estructura y actividad biológica

AA CORONA - 2021 - riaa.uaem.mx
Desde su nacimiento, el desarrollo de la química macrocíclica ha seguido dos líneas: 4
como modelos de los sistemas macrocíclicos naturales, que contienen predominantemente …